Results of the European Group for the Study of Resistant Depression (GSRD)—basis for further research and clinical practice
Objectives: The overview outlines two decades of research from the European Group for the
Study of Resistant Depression (GSRD) that fundamentally impacted evidence-based …
Study of Resistant Depression (GSRD) that fundamentally impacted evidence-based …
Does pharmacogenomic testing improve clinical outcomes for major depressive disorder? A systematic review of clinical trials and cost-effectiveness studies
JD Rosenblat, Y Lee, RS McIntyre - The Journal of clinical …, 2017 - psychiatrist.com
Objective: Pharmacogenomic testing has become scalable and available to the general
public. Pharmacogenomics has shown promise for predicting antidepressant response and …
public. Pharmacogenomics has shown promise for predicting antidepressant response and …
The promise of machine learning in predicting treatment outcomes in psychiatry
For many years, psychiatrists have tried to understand factors involved in response to
medications or psychotherapies, in order to personalize their treatment choices. There is …
medications or psychotherapies, in order to personalize their treatment choices. There is …
Is AI the future of mental healthcare?
F Minerva, A Giubilini - Topoi, 2023 - Springer
Over the past decade, AI has been used to aid or even replace humans in many
professional fields. There are now robots delivering groceries or working in assembling lines …
professional fields. There are now robots delivering groceries or working in assembling lines …
An inflammatory biomarker as a differential predictor of outcome of depression treatment with escitalopram and nortriptyline
Objective: Major depressive disorder has been linked with inflammatory processes, but it is
unclear whether individual differences in levels of inflammatory biomarkers could help …
unclear whether individual differences in levels of inflammatory biomarkers could help …
Pharmacogenetic tests and depressive symptom remission: a meta-analysis of randomized controlled trials
CA Bousman, K Arandjelovic, SG Mancuso… - …, 2019 - Taylor & Francis
Aim: To conducted a systematic review and meta-analysis of prospective, randomized
controlled trials (RCTs) that examined pharmacogenetic-guided decision support tools …
controlled trials (RCTs) that examined pharmacogenetic-guided decision support tools …
Efficacy of prospective pharmacogenetic testing in the treatment of major depressive disorder: results of a randomized, double-blind clinical trial
V Pérez, A Salavert, J Espadaler, M Tuson, J Saiz-Ruiz… - BMC psychiatry, 2017 - Springer
Abstract Background A 12-week, double-blind, parallel, multi-center randomized controlled
trial in 316 adult patients with major depressive disorder (MDD) was conducted to evaluate …
trial in 316 adult patients with major depressive disorder (MDD) was conducted to evaluate …
[HTML][HTML] Improved efficacy with targeted pharmacogenetic-guided treatment of patients with depression and anxiety: a randomized clinical trial demonstrating clinical …
P Bradley, M Shiekh, V Mehra, K Vrbicky… - Journal of psychiatric …, 2018 - Elsevier
The objective of this study was to evaluate the effect of pharmacogenetics-guided treatment
on patients diagnosed with depression and/or anxiety, in a diverse set of clinical settings, as …
on patients diagnosed with depression and/or anxiety, in a diverse set of clinical settings, as …
Optimizing prediction of response to antidepressant medications using machine learning and integrated genetic, clinical, and demographic data
Major depressive disorder (MDD) is complex and multifactorial, posing a major challenge of
tailoring the optimal medication for each patient. Current practice for MDD treatment mainly …
tailoring the optimal medication for each patient. Current practice for MDD treatment mainly …
Clinical implementation of pharmacogenetic decision support tools for antidepressant drug prescribing
The accrual and analysis of genomic sequencing data have identified specific genetic
variants that are associated with major depressive disorder. Moreover, substantial …
variants that are associated with major depressive disorder. Moreover, substantial …