Molecular principles of hair follicle induction and morphogenesis

R Schmidt‐Ullrich, R Paus - Bioessays, 2005 - Wiley Online Library
Hair follicle (HF) development is the result of neuroectodermal–mesodermal interactions,
and can be divided into morphologically distinguishable stages (induction, organogenesis …

[HTML][HTML] Molecular control of epithelial–mesenchymal interactions during hair follicle cycling

VA Botchkarev, J Kishimoto - Journal of Investigative Dermatology …, 2003 - Elsevier
Epithelial–mesenchymal interactions play pivotal roles in the morphogenesis of many
organs and various types of appendages. During hair follicle development, extensive …

Integrated single-cell chromatin and transcriptomic analyses of human scalp identify gene-regulatory programs and critical cell types for hair and skin diseases

B Ober-Reynolds, C Wang, JM Ko, EJ Rios, SZ Aasi… - Nature Genetics, 2023 - nature.com
Genome-wide association studies have identified many loci associated with hair and skin
disease, but identification of causal variants requires deciphering of gene-regulatory …

Hox specificity: unique roles for cofactors and collaborators

RS Mann, KM Lelli, R Joshi - Current topics in developmental biology, 2009 - Elsevier
Hox proteins are well known for executing highly specific functions in vivo, but our
understanding of the molecular mechanisms underlying gene regulation by these …

[HTML][HTML] Beta-caryophyllene enhances wound healing through multiple routes

S Koyama, A Purk, M Kaur, HA Soini, MV Novotny… - PloS one, 2019 - journals.plos.org
Beta-caryophyllene is an odoriferous bicyclic sesquiterpene found in various herbs and
spices. Recently, it was found that beta-caryophyllene is a ligand of the cannabinoid …

Human hair keratin‐associated proteins (KAPs)

MA Rogers, L Langbein, S Praetzel‐Wunder… - International review of …, 2006 - Elsevier
Elucidation of the genes encoding structural proteins of the human hair follicle has
advanced rapidly during the last decade, complementing nearly three previous decades of …

Defining BMP functions in the hair follicle by conditional ablation of BMP receptor IA

K Kobielak, HA Pasolli, L Alonso, L Polak… - The Journal of cell …, 2003 - rupress.org
Using conditional gene targeting in mice, we show that BMP receptor IA is essential for the
differentiation of progenitor cells of the inner root sheath and hair shaft. Without BMPRIA …

Molecular biology of hair morphogenesis: development and cycling

VA Botchkarev, R Paus - Journal of Experimental Zoology Part …, 2003 - Wiley Online Library
In mammals, hair follicles produce hairs that fulfill a number of functions including
thermoregulation, collecting sensory information, protection against environmental trauma …

[HTML][HTML] Micro-RNA-31 controls hair cycle-associated changes in gene expression programs of the skin and hair follicle

AN Mardaryev, MI Ahmed, NV Vlahov… - The FASEB …, 2010 - ncbi.nlm.nih.gov
The hair follicle is a cyclic biological system that progresses through stages of growth,
regression, and quiescence, which involves dynamic changes in a program of gene …

Single-cell profiling reveals a potent role of quercetin in promoting hair regeneration

Q Zhao, Y Zheng, D Zhao, L Zhao, L Geng, S Ma… - Protein & …, 2023 - academic.oup.com
Hair loss affects millions of people at some time in their life, and safe and efficient treatments
for hair loss are a significant unmet medical need. We report that topical delivery of quercetin …