Francisella tularensis is a zoonotic intracellular pathogen and the causative agent of the
debilitating febrile illness tularemia. Although natural infections by F. tularensis are sporadic …

Francisella tularensis is a facultative intracellular gram-negative pathogen and the
etiological agent of the zoonotic disease tularemia. Recent advances in the field of …

Background Francisella tularensis subspecies tularensis and holarctica are pathogenic to
humans, whereas the two other subspecies, novicida and mediasiatica, rarely cause …

Francisella tularensis is a Gram-negative intracellular pathogen and the causative agent of
the disease tularemia. Inhalation of as few as 10 bacteria is sufficient to cause severe …

Burkholderia pseudomallei causes the disease melioidosis in humans and is classified as a
category B select agent. Research utilizing this pathogen is highly regulated in the United …

Borrelia burgdorferi, the aetiological agent of Lyme disease, follows a life cycle that involves
passage between the tick vector and the mammalian host. To investigate the role of the 36 …

The tularemia-causing bacterium Francisella tularensis is a facultative intracellular organism
with a complex intracellular lifecycle that ensures its survival and proliferation in a variety of …

Francisella tularensis, the highly virulent etiologic agent of tularemia, is a low-dose
intracellular pathogen that is able to escape from the phagosome and replicate in the …

Francisella tularensis is one of the most pathogenic pathogens known, especially when
disseminated as a small particle aerosol. Because of this, it was developed into a biological …

Over the last decade, studies on the virulence of the highly pathogenic intracellular bacterial
pathogen Francisella tularensis have increased dramatically. The organism produces an …