The first studies suggesting that abnormal expression of galectins is associated with cancer
were published more than 30 years ago. Today, the role of galectins in cancer is relatively …

Among all the biological entities involved in the immune response, galectins, a family of
glycan-binding proteins, have been described as key in immune cell homeostasis and …

Galectins comprise a family of soluble β-galactoside-binding proteins, which regulate a
variety of key biological processes including cell growth, differentiation, survival, and death …

Lectin-glycan interactions, in particular those mediated by the galectin family, regulate many
processes required for a successful pregnancy. Over the past decades, increasing evidence …

Although considerable attention has been paid to the role of extracellular galectins in
modulating, positively or negatively, tumor growth and metastasis, we have witnessed a …

In humans, a total of 12 galectins have been identified. Their intracellular and extracellular
biological functions are explored and discussed in this review. These galectins play …

Galectin-7 is a soluble unglycosylated lectin that is able to bind specifically to β-
galactosides. It has been described to be involved in apoptosis, proliferation and …

Metastasis predicts poor prognosis in cancer patients. It has been recognized that specific
tumor microenvironment defines cancer cell metastasis, whereas the underlying …

Human lectins are integral to maintaining microbial homeostasis on the skin, in the blood,
and at mucosal barriers. These proteins can recognize microbial glycans and inform the host …

Stroke, whether ischemic or haemorrhagic, is one of the main causes of mortality and
disability all over the world, which entails huge burdens in both healthcare environments as …