Placental galectins in cancer: why we should pay more attention
C Fuselier, A Dumoulin, A Paré, R Nehmé, S Ajarrag… - Cells, 2023 - mdpi.com
The first studies suggesting that abnormal expression of galectins is associated with cancer
were published more than 30 years ago. Today, the role of galectins in cancer is relatively …
were published more than 30 years ago. Today, the role of galectins in cancer is relatively …
[HTML][HTML] Therapeutic potential of targeting galectins–A biomaterials-focused perspective
Among all the biological entities involved in the immune response, galectins, a family of
glycan-binding proteins, have been described as key in immune cell homeostasis and …
glycan-binding proteins, have been described as key in immune cell homeostasis and …
Expression, regulation, and functions of the galectin-16 gene in human cells and tissues
JD Kaminker, AV Timoshenko - Biomolecules, 2021 - mdpi.com
Galectins comprise a family of soluble β-galactoside-binding proteins, which regulate a
variety of key biological processes including cell growth, differentiation, survival, and death …
variety of key biological processes including cell growth, differentiation, survival, and death …
Medawar's PostEra: galectins emerged as key players during fetal-maternal glycoimmune adaptation
E Menkhorst, NG Than, U Jeschke… - Frontiers in …, 2021 - frontiersin.org
Lectin-glycan interactions, in particular those mediated by the galectin family, regulate many
processes required for a successful pregnancy. Over the past decades, increasing evidence …
processes required for a successful pregnancy. Over the past decades, increasing evidence …
Targeting intracellular galectins for cancer treatment
R Nehmé, Y St-Pierre - Frontiers in Immunology, 2023 - frontiersin.org
Although considerable attention has been paid to the role of extracellular galectins in
modulating, positively or negatively, tumor growth and metastasis, we have witnessed a …
modulating, positively or negatively, tumor growth and metastasis, we have witnessed a …
Chimera and tandem-repeat type galectins: the new targets for cancer immunotherapy
FCF Ko, S Yan, KW Lee, SK Lam, JCM Ho - Biomolecules, 2023 - mdpi.com
In humans, a total of 12 galectins have been identified. Their intracellular and extracellular
biological functions are explored and discussed in this review. These galectins play …
biological functions are explored and discussed in this review. These galectins play …
Functions and inhibition of galectin-7, an emerging target in cellular pathophysiology
NV Sewgobind, S Albers, RJ Pieters - Biomolecules, 2021 - mdpi.com
Galectin-7 is a soluble unglycosylated lectin that is able to bind specifically to β-
galactosides. It has been described to be involved in apoptosis, proliferation and …
galactosides. It has been described to be involved in apoptosis, proliferation and …
Identification of Galectin-7 as a crucial metastatic enhancer of squamous cell carcinoma associated with immunosuppression
J An, Y Nagaki, S Motoyama, Y Kuze, M Hoshizaki… - Oncogene, 2022 - nature.com
Metastasis predicts poor prognosis in cancer patients. It has been recognized that specific
tumor microenvironment defines cancer cell metastasis, whereas the underlying …
tumor microenvironment defines cancer cell metastasis, whereas the underlying …
Soluble Human Lectins at the Host–Microbe Interface
AL Peiffer, AE Dugan… - Annual Review of …, 2024 - annualreviews.org
Human lectins are integral to maintaining microbial homeostasis on the skin, in the blood,
and at mucosal barriers. These proteins can recognize microbial glycans and inform the host …
and at mucosal barriers. These proteins can recognize microbial glycans and inform the host …
Galectin‐3: A Novel Marker for the Prediction of Stroke Incidence and Clinical Prognosis
Stroke, whether ischemic or haemorrhagic, is one of the main causes of mortality and
disability all over the world, which entails huge burdens in both healthcare environments as …
disability all over the world, which entails huge burdens in both healthcare environments as …