[HTML][HTML] Translating complexity and heterogeneity of pancreatic tumor: 3D in vitro to in vivo models
MA Heinrich, AMRH Mostafa, JP Morton… - Advanced drug delivery …, 2021 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC) is an extremely aggressive type of cancer with
an overall survival rate of less than 7-8%, emphasizing the need for novel effective …
an overall survival rate of less than 7-8%, emphasizing the need for novel effective …
Devices and techniques used to obtain and analyze three‐dimensional cell cultures
G Agrawal, A Ramesh, P Aishwarya… - Biotechnology …, 2021 - Wiley Online Library
Cell cultures are indispensable for both basic and applied research. Advancements in cell
culture and analysis increase their utility for basic research and translational applications. A …
culture and analysis increase their utility for basic research and translational applications. A …
Calcium, mitochondria and the initiation of acute pancreatitis
SJ Pandol, RA Gottlieb - Pancreatology, 2022 - Elsevier
Acute pancreatitis is characterized by necrosis of its parenchymal cells and influx and
activation of inflammatory cells that further promote injury and necrosis. This review is …
activation of inflammatory cells that further promote injury and necrosis. This review is …
Animal models to study the role of pulmonary intravascular macrophages in spontaneous and induced acute pancreatitis
V Vrolyk, B Singh - Cell and tissue research, 2020 - Springer
Acute necrotizing pancreatitis (ANP) is a common gastrointestinal cause of emergency
admissions in dogs and humans and can lead to a systemic inflammatory response …
admissions in dogs and humans and can lead to a systemic inflammatory response …
Chemical pancreatectomy treats chronic pancreatitis while preserving endocrine function in preclinical models
Chronic pancreatitis affects over 250,000 people in the US and millions worldwide. It is
associated with chronic debilitating pain, pancreatic exocrine failure, and high risk of …
associated with chronic debilitating pain, pancreatic exocrine failure, and high risk of …
[HTML][HTML] Experimental pancreatitis is characterized by rapid T cell activation, Th2 differentiation that parallels disease severity, and improvement after CD4+ T cell …
J Glaubitz, A Wilden, C van den Brandt, FU Weiss… - Pancreatology, 2020 - Elsevier
Background Acute pancreatitis is a gastrointestinal disorder of high incidence resulting in life
threatening complications in up to 20% of patients. Its severe form is characterized by an …
threatening complications in up to 20% of patients. Its severe form is characterized by an …
Xiao Chai Hu Tang alleviates the pancreatic tumorigenesis via improving the mtDNA N6-Methyladenine modification mediated mitochondrial dysfunction in Syrian …
J Cai, W Shen, G Zhang, X Li, H Shen, W Li, C Tan… - Phytomedicine, 2023 - Elsevier
Abstract Background Pancreatic intraepithelial neoplasia (PanIN) is the most common
precursor lesion of pancreatic ductal adenocarcinoma (PDAC), which is a highly malignant …
precursor lesion of pancreatic ductal adenocarcinoma (PDAC), which is a highly malignant …
Barriers and research priorities for implementing precision medicine
DC Whitcomb - Pancreas, 2019 - journals.lww.com
The vision of precision medicine is to prescribe the right treatment to the right patient in the
right dose at the right time and to expect the optimal outcome. 1 Precision medicine, as …
right dose at the right time and to expect the optimal outcome. 1 Precision medicine, as …
Serum biomarkers for chronic pancreatitis pain patterns
Objectives Chronic pancreatitis (CP) is associated with debilitating refractory pain. Distinct
subtypes of CP pain have been previously characterized based on severity (none, mild …
subtypes of CP pain have been previously characterized based on severity (none, mild …
Uncovering the pharmacology of Xiaochaihu decoction in the treatment of acute pancreatitis based on the network pharmacology
L Zhan, J Pu, Y Hu, P Xu, W Liang… - BioMed Research …, 2021 - Wiley Online Library
Background. Xiaochaihu decoction (XD) has demonstrated the pharmacodynamics on acute
pancreatitis. This study was aimed at investigating the material and molecular basis of …
pancreatitis. This study was aimed at investigating the material and molecular basis of …