Engineering mesoporous silica nanoparticles for drug delivery: where are we after two decades?

M Vallet-Regí, F Schüth, D Lozano, M Colilla… - Chemical Society …, 2022 - pubs.rsc.org
The present review details a chronological description of the events that took place during
the development of mesoporous materials, their different synthetic routes and their use as …

Targeting nanoparticles for diagnosis and therapy of bone tumors: Opportunities and challenges

X Gao, L Li, X Cai, Q Huang, J Xiao, Y Cheng - Biomaterials, 2021 - Elsevier
A variety of targeted nanoparticles were developed for the diagnosis and therapy of
orthotopic and metastatic bone tumors during the past decade. This critical review will focus …

Bone-targeted biomaterials: Strategies and applications

X Ren, X Chen, Z Geng, J Su - Chemical Engineering Journal, 2022 - Elsevier
Bone diseases including osteoarthritis, osteoporosis, and bone tumors are becoming severe
threats to public health. Bone-targeted biomaterials-based strategies could improve …

Mesoporous silica nanoparticles for tissue‐engineering applications

L Chen, X Zhou, C He - Wiley Interdisciplinary Reviews …, 2019 - Wiley Online Library
Mesoporous silica nanoparticles (MSNs) have been widely investigated as a nanocarrier for
the delivery of various cargoes in nanomedicine. The application of MSNs in tissue …

Mesoporous silica nanoparticles for the treatment of complex bone diseases: Bone cancer, bone infection and osteoporosis

M Gisbert-Garzarán, M Manzano, M Vallet-Regí - Pharmaceutics, 2020 - mdpi.com
Bone diseases, such as bone cancer, bone infection and osteoporosis, constitute a major
issue for modern societies as a consequence of their progressive ageing. Even though …

Dendritic fibrous nano-particles (DFNPs): rising stars of mesoporous materials

Y Wang, X Du, Z Liu, S Shi, H Lv - Journal of materials chemistry A, 2019 - pubs.rsc.org
Dendritic fibrous nano-particles (DFNPs) with three-dimensional (3D) center-radial channels
and hierarchical pores have unique structural characteristics including open pore …

Peritumoral microgel reservoir for long‐term light‐controlled triple‐synergistic treatment of osteosarcoma with single ultra‐low dose

J Yan, Y Wang, M Ran, RA Mustafa, H Luo, J Wang… - Small, 2021 - Wiley Online Library
Local minimally invasive injection of anticancer therapies is a compelling approach to
maximize the utilization of drugs and reduce the systemic adverse drug effects. However, the …

Rare earth-based materials for bone regeneration: breakthroughs and advantages

Y Huang, X Zhai, T Ma, M Zhang, H Pan, WW Lu… - Coordination Chemistry …, 2022 - Elsevier
As a remarkable strategic resource, rare earth elements (REEs) endow implantable bone
regeneration materials with excellent properties both in vitro and in vivo, including …

Additive manufacturing of polymer/bioactive glass scaffolds for regenerative medicine: a review

A Martelli, D Bellucci, V Cannillo - Polymers, 2023 - mdpi.com
Tissue engineering (TE) is a branch of regenerative medicine with enormous potential to
regenerate damaged tissues using synthetic grafts such as scaffolds. Polymers and …

Mesoporous silica based nanostructures for bone tissue regeneration

S Ghosh, TJ Webster - Frontiers in Materials, 2021 - frontiersin.org
Porous nano-scaffolds provide for better opportunities to restore, maintain, and improve
functions of damaged tissues and organs by facilitating tissue regeneration. Various …