Primary hypothyroidism and Alzheimer's Disease: a tale of two

FH AlAnazi, HM Al-Kuraishy, A Alexiou… - Cellular and Molecular …, 2023 - Springer
Hypothyroidism (HPT) HPT could be a risk factor for the development and progression of
Alzheimer's disease (AD). In addition, progressive neurodegeneration in AD may affect the …

Thyroid hormone distributor proteins during development in vertebrates

SA Rabah, IL Gowan, M Pagnin, N Osman… - Frontiers in …, 2019 - frontiersin.org
Thyroid hormones (THs) are ancient hormones that not only influence the growth,
development and metabolism of vertebrates but also affect the metabolism of (at least some) …

Thyroid disruption by triphenyl phosphate, an organophosphate flame retardant, in zebrafish (Danio rerio) embryos/larvae, and in GH3 and FRTL-5 cell lines

S Kim, J Jung, I Lee, D Jung, H Youn, K Choi - Aquatic Toxicology, 2015 - Elsevier
Triphenyl phosphate (TPP), one of the most widely used organophosphate flame retardants
(OPFRs), has frequently been detected in the environment and biota. However, knowledge …

Bioconcentration, biotransformation, and thyroid endocrine disruption of decabromodiphenyl ethane (Dbdpe), a novel brominated flame retardant, in zebrafish larvae

X Wang, S Ling, K Guan, X Luo, L Chen… - … science & technology, 2019 - ACS Publications
The brominated flame retardant decabromodiphenyl ethane (DBDPE), an alternative to
decabrominated diphenyl ether (BDE209), has become a widespread environmental …

[HTML][HTML] Thyroid endocrine disruption in zebrafish larvae following exposure to hexaconazole and tebuconazole

L Yu, M Chen, Y Liu, W Gui, G Zhu - Aquatic toxicology, 2013 - Elsevier
The widely used triazole fungicides have the potential to disrupt endocrine system, but little
is known of such effects or underlying mechanisms of hexaconazole (HEX) and …

Comparison of developmental toxicity induced by PFOA, HFPO-DA, and HFPO-TA in zebrafish embryos

Y Wang, S Jiang, B Wang, X Chen, G Lu - Chemosphere, 2023 - Elsevier
Hexafluoropropylene oxide dimer acids (HFPO-DA) and hexafluoropropylene oxide trimer
acids (HFPO-TA) are alternatives to perfluorooctanoic acid (PFOA). However, little …

Bioconcentration and metabolism of decabromodiphenyl ether (BDE-209) result in thyroid endocrine disruption in zebrafish larvae

Q Chen, L Yu, L Yang, B Zhou - Aquatic toxicology, 2012 - Elsevier
Polybrominated diphenyl ethers (PBDEs) have the potential to disturb the thyroid endocrine
system, but little is known of such effects or underlying mechanisms of BDE-209 in fish. In …

Waterborne exposure to PFOS causes disruption of the hypothalamus–pituitary–thyroid axis in zebrafish larvae

X Shi, C Liu, G Wu, B Zhou - Chemosphere, 2009 - Elsevier
Thyroid hormones (THs) play an important role in the normal development and physiological
functions in fish. Environmental chemicals may adversely affect thyroid function by disturbing …

[HTML][HTML] Perfluorohexanoic acid caused disruption of the hypothalamus-pituitary-thyroid axis in zebrafish larvae

S Zhang, X Guo, S Lu, J He, Q Wu, X Liu, Z Han… - Ecotoxicology and …, 2022 - Elsevier
Highlights•Zebrafish embryos were exposed to different concentrations of PFHxA for 96
hpf.•PFHxA exposure resulted in decrease of tshβ contents in zebrafish larvae.•Alterations of …

The effects of disturbance on hypothalamus-pituitary-thyroid (HPT) axis in zebrafish larvae after exposure to DEHP

PP Jia, YB Ma, CJ Lu, Z Mirza, W Zhang, YF Jia, WG Li… - PloS one, 2016 - journals.plos.org
Di-(2-ethylhexyl) phthalate (DEHP) has the potential to disrupt the thyroid endocrine system,
but the underlying mechanism is unknown. In this study, zebrafish (Danio rerio) embryos …