Malaria is one of the most devastating infectious diseases of humans. It is problematic
clinically and economically as it prevails in poorer countries and regions, strongly hindering …

Chagas disease (CD) is a parasitic, systemic, chronic, and often fatal illness caused by
infection with the protozoan Trypanosoma cruzi. The World Health Organization classifies …

The ability of the Chagas disease agent Trypanosoma cruzi to resist extended in vivo
exposure to highly effective trypanocidal compounds prompted us to explore the potential for …

Malaria, which is caused by Plasmodium spp., starts with an asymptomatic phase, during
which sporozoites, the parasite form that is injected into the skin by a mosquito, develop into …

Abstract “The Primate Malarias” book has been a uniquely important resource for multiple
generations of scientists, since its debut in 1971, and remains pertinent to the present day …

The protozoan Trypanosoma cruzi is the causative agent of Chagas disease, a neglected
tropical disease that affects around 8 million people worldwide. Chagas disease can be …

The homodimeric flavoenzyme glutathione reductase catalyzes NADPH-dependent
glutathione disulfide reduction. This reaction is important for keeping the redox homeostasis …

The concept that hypnozoites give rise to relapses in Plasmodium vivax and Plasmodium
ovale malaria has become dogma. However, it is evident from particular contemporary …

A curious aspect of the evolution of the hypnozoite theory of malarial relapse is its
transmogrification from theory into 'fact', this being of historical, linguistic, scientific and …

Enhanced therapeutic efficacy achieved in treating Plasmodium vivax malaria with an 8-
aminoquinoline (8-AQ) drug such as primaquine (PQ) together with a partner drug such as …