Recent advances of NFATc1 in rheumatoid arthritis-related bone destruction: mechanisms and potential therapeutic targets

H Zheng, Y Liu, Y Deng, Y Li, S Liu, Y Yang, Y Qiu… - Molecular …, 2024 - Springer
Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease characterized by
inflammation of the synovial tissue and joint bone destruction, often leading to significant …

NFAM1 Promotes pro-inflammatory cytokine production in mouse and human monocytes

KW Juchem, AP Gounder, JP Gao… - Frontiers in …, 2022 - frontiersin.org
NFAT activating protein with ITAM motif 1 (NFAM1) is an ITAM bearing-transmembrane
receptor that has been reported to play a role in B cell signaling and development. We …

Cryoprotective isoliquiritigenin-zein phosphatidylcholine nanoparticles inhibits breast cancer-bone metastasis by targeting JAK-STAT signaling pathways

K Ganesan, C Xu, C Xie, Y Sui, C Zheng, F Gao… - Chemico-Biological …, 2024 - Elsevier
Breast cancer (BC) is the most common cancer in women and is known for its tendency to
spread to the bones, causing significant health issues and mortality. In this study, we aimed …

Impact of dual neutralization of TNF-α and IL-1β along with Gentamicin treatment on the functions of blood and splenic neutrophils and its role on improvement of S …

S Ghosh, R Ghosh, R Sawoo, P Dutta… - International …, 2023 - Elsevier
Researches of recent past years have emphasized potential of antibiotics to improve septic
arthritis but as multi-drug resistant strains like MRSA are emerging fast, new alternative …