Antimicrobial resistance: a growing serious threat for global public health

MA Salam, MY Al-Amin, MT Salam, JS Pawar, N Akhter… - Healthcare, 2023 - mdpi.com
Antibiotics are among the most important discoveries of the 20th century, having saved
millions of lives from infectious diseases. Microbes have developed acquired antimicrobial …

Antibiotic resistance mechanisms in bacteria: relationships between resistance determinants of antibiotic producers, environmental bacteria, and clinical pathogens

E Peterson, P Kaur - Frontiers in microbiology, 2018 - frontiersin.org
Emergence of antibiotic resistant pathogenic bacteria poses a serious public health
challenge worldwide. However, antibiotic resistance genes are not confined to the clinic; …

[HTML][HTML] An overview of the antimicrobial resistance mechanisms of bacteria

WC Reygaert - AIMS microbiology, 2018 - ncbi.nlm.nih.gov
Resistance to antimicrobial agents has become a major source of morbidity and mortality
worldwide. When antibiotics were first introduced in the 1900's, it was thought that we had …

Emergent crisis of antibiotic resistance: A silent pandemic threat to 21st century

F Akram, M Imtiaz, I ul Haq - Microbial pathogenesis, 2023 - Elsevier
Antibiotic resistance has become an indispensably alarming menace to the global
community. The primary factors are overuse and abuse of antibiotics, lack of novel …

Antimicrobial resistance

L Morrison, TR Zembower - Gastrointestinal Endoscopy …, 2020 - giendo.theclinics.com
Given recent media attention, it would be easy to assume that antimicrobial resistance is a
new problem; however, antimicrobial resistance has existed well before antimicrobials were …

Antibiotic discovery and resistance: the chase and the race

K Iskandar, J Murugaiyan, D Hammoudi Halat… - Antibiotics, 2022 - mdpi.com
The history of antimicrobial resistance (AMR) evolution and the diversity of the
environmental resistome indicate that AMR is an ancient natural phenomenon. Acquired …

Sequencing-based methods and resources to study antimicrobial resistance

M Boolchandani, AW D'Souza, G Dantas - Nature Reviews Genetics, 2019 - nature.com
Antimicrobial resistance extracts high morbidity, mortality and economic costs yearly by
rendering bacteria immune to antibiotics. Identifying and understanding antimicrobial …

The antibiotic resistome: a guide for the discovery of natural products as antimicrobial agents

C Hobson, AN Chan, GD Wright - Chemical Reviews, 2021 - ACS Publications
The use of life-saving antibiotics has long been plagued by the ability of pathogenic bacteria
to acquire and develop an array of antibiotic resistance mechanisms. The sum of these …

Molecular mechanisms of biofilm-based antibiotic resistance and tolerance in pathogenic bacteria

CW Hall, TF Mah - FEMS microbiology reviews, 2017 - academic.oup.com
Biofilms are surface-attached groups of microbial cells encased in an extracellular matrix
that are significantly less susceptible to antimicrobial agents than non-adherent, planktonic …

Antibacterial drug discovery in the resistance era

ED Brown, GD Wright - Nature, 2016 - nature.com
The looming antibiotic-resistance crisis has penetrated the consciousness of clinicians,
researchers, policymakers, politicians and the public at large. The evolution and widespread …