The past 20 years have seen enormous progress in the understanding of the mechanisms
used by the enteric bacterium Escherichia coli to promote protein folding, support protein …

Progress in our understanding of several biological processes promises to broaden the
usefulness of Escherichia coli as a tool for gene expression. There is an expanding choice …

▪ Abstract Proteolysis in Escherichia coli serves to rid the cell of abnormal and misfolded
proteins and to limit the time and amounts of availability of critical regulatory proteins. Most …

Misfolding or unfolding of polypeptides can occur as a consequence of environmental stress
and spontaneous mutation. The abundance of general chaperones and proteases suggests …

Cells precisely monitor the concentration and functionality of each protein for optimal
performance. Protein quality control involves molecular chaperones, folding catalysts, and …

A list of currently identified gene products of Escherichia coli is given, together with a
bibliography that provides pointers to the literature on each gene product. A scheme to …

The temperature inducible expression system, based on the pL and/or pR phage lambda
promoters regulated by the thermolabile cI857 repressor has been widely use to produce …

Protein quality control involves sensing and treatment of defective or incomplete protein
structures. Misfolded or mislocalized proteins trigger dedicated signal transduction cascades …

The invention relates to methods of producing recombinant polypeptides in protease-de?
cient bacterial hosts. Con structs of single, double, triple and quadruple protease de? cient …

The HtrA proteases degrade damaged proteins and thus control the quality of proteins and
protect cells against the consequences of various stresses; they also recognize specific …