Aging promotes chronic inflammation, which contributes to fibrosis and decreases organ
function. Fibrosis, the excessive synthesis and deposition of extracellular matrix …

Abstract The Yangtze River, the third largest river and supporting nearly one-third of
Chinese population, has been severely polluted in recent decades. Among the numerous …

The aryl hydrocarbon receptor (AhR) is a transcript factor, belonging to the basic helix-loop-
helix-Per-ARNT-SIM family, is closely associated with health and diseases. Targeting AhR is …

Ligand-specific binding interactions of xenobiotics with receptor proteins form the basis of
cytotoxicity-based hazard assessment. Computational approaches enable predictive hazard …

The question behind all works presented in this thesis is “why do similarly structured
molecules exhibit distinct carcinogenic behaviors?” Answering this question is important to …

Present work describes the DFT studies of?-(N-Benzoxazolin-2-one) acetic acid and its
solvate with formic acid comparing to N-benzoxazoline-2-one and 2-aminoacetic acid. The …