Recent advances in cell-type deconvolution approaches are adding to our understanding of
the biology underlying disease development and progression. DNA methylation (DNAm) …

Worldwide, smoking remains a threat to public health, causing preventable diseases and
premature mortality. Cigarette smoke is a powerful inducer of DNA methylation and gene …

Long-term exposure to air pollution has been associated with several adverse health effects
including cardiovascular, respiratory diseases and cancers. However, underlying molecular …

Understanding mediation is useful for identifying intermediates lying between an exposure
and an outcome which, when intervened upon, will block (some or all of) the causal pathway …

Air pollution is associated with a broad range of adverse health effects, including mortality
and morbidity due to cardio‐and cerebrovascular diseases (CCVD), but the molecular …

Traffic-related air pollution is a complex mixture of particulate matter (PM) and gaseous
pollutants, such as nitrogen dioxide (NO2). PM exposure contributes to the pathogenesis of …

Exposure to environmental stressors, toxicants, and nutrient deficiencies can affect DNA in
several ways. Some exposures cause damage and alter the structure of DNA, but there is …

Background Multiple omics technologies are increasingly applied to detect early, subtle
molecular responses to environmental stressors for future disease risk prevention. However …

Increasing evidence points to a role for inflammation in lung carcinogenesis. A small number
of circulating inflammatory proteins have been identified as showing elevated levels prior to …

For their stability and detectability faecal microRNAs represent promising molecules with
potential clinical interest as non-invasive diagnostic and prognostic biomarkers. However …