The impact of proteins and peptides on the treatment of various conditions including ocular
diseases over the past few decades has been advanced by substantial breakthroughs in …

Rheumatoid arthritis (RA) is a chronic autoimmune disease that is considered to be one of
the major public health problems worldwide. The development of therapies that target tumor …

Abstract Poly (amidoamine)(PAMAM) dendrimers, as a family of synthetic macromolecules
with highly branched interiors, abundant surface functional groups, and well-controlled …

Glioblastoma (GB) is a grade IV astrocytoma that maintains a poor prognosis with respect to
current treatment options. Despite major advancements in the fields of surgery and …

Glioblastoma (GB) is the most lethal type of primary tumor in the central nervous system.
Current treatments include surgical resection followed by chemotherapy and radiotherapy …

Glioblastoma (GBM), the most common primary malignant brain tumor, is associated with a
dismal prognosis. Standard therapies including maximal surgical resection, radiotherapy …

The use of monolabeled tumor-targeting peptides for molecular imaging is widespread.
However, it is often desirable to use the same compound for different clinical applications …

Selective targeting of anticancer drugs to the tumor site is critical for effective cancer therapy.
The cell adhesion molecule integrin α vβ 3 is not readily detectable in quiescent vessels but …

Multivalent interactions of biological molecules play an important role in many biochemical
events. A multivalent ligand comprises of multiple copies of ligands conjugated to scaffolds …

Dendrimers comprise a category of branched materials with diverse functions that can be
constructed with defined architectural and chemical structures. When decorated with …