DNA methylation is a conserved epigenetic modification that is important for gene regulation
and genome stability. Aberrant patterns of DNA methylation can lead to plant developmental …

Highlights•GbM is typified by mCG within coding regions, and depletion at the TSS and
TTS.•Species without gbM revealed an unexpected role for CMT3 in the evolution of …

A contribution of DNA methylation to defense against invading nucleic acids and
maintenance of genome integrity is uncontested; however, our understanding of the extent …

Understanding genomic functions requires site-specific manipulation of loci via efficient
protein effector targeting systems. However, few approaches for targeted manipulation of the …

Glyphosate is the most widely used herbicide in world agriculture and for general vegetation
control in a wide range of situations. Global and often intensive glyphosate selection of very …

Conifers have dominated forests for more than 200 million years and are of huge ecological
and economic importance. Here we present the draft assembly of the 20-gigabase genome …

In plants, cytosine DNA methylations (5mCs) can happen in three sequence contexts as
CpG, CHG, and CHH (where H= A, C, or T), which play different roles in the regulation of …

Cytosine DNA methylation is a stable epigenetic mark that is crucial for diverse biological
processes, including gene and transposon silencing, imprinting and X chromosome …

Eukaryotic cytosine methylation represses transcription but also occurs in the bodies of
active genes, and the extent of methylation biology conservation is unclear. We quantified …

Over the last decade,∼ 20–30 nucleotide RNA molecules have emerged as critical
regulators in the expression and function of eukaryotic genomes. Two primary categories of …