Osteoarthritis (OA) is a leading cause of pain and disability worldwide. Despite the existence
of evidence-based treatments and guidelines, substantial gaps remain in the quality of OA …

Background The addition of vancomycin to beta-lactam prophylaxis in arthroplasty may
reduce surgical-site infections; however, the efficacy and safety are unclear. Methods In this …

Background: Elective total hip arthroplasty (THA) and total knee arthroplasty (TKA) are
effective options for the management of osteoarthritis that has not responded to conservative …

Background In contrast to best practice guidelines for knee osteoarthritis (OA), findings from
several different healthcare settings have identified that nonsurgical treatments are …

Abstract Background The Affordable Care Act of 2010 advanced the economic model of
bundled payments for total joint arthroplasty (TJA), in which hospitals will be financially …

Background In the emerging fiscal climate of value-based decision-making and shared risk
and remuneration, outpatient total joint arthroplasty is attractive provided the incidence of …

Background Current estimates for the direct costs of a single episode of care for
periprosthetic joint infection (PJI) after THA are approximately USD 100,000. These …

Background Although total hip arthroplasty (THA) has been established as a cost-effective
intervention, some patients experience ongoing pain and dissatisfaction. There is interest in …

Background Indications for total knee arthroplasty (TKA) currently depend on clinical
judgment. Up to one fifth of those who undergo primary TKA do not report a clinically …

Aims To calculate how the likelihood of obtaining measurable benefit from hip or knee
arthroplasty varies with preoperative patient-reported scores. Methods Existing UK data from …