Mass spectrometry-based techniques to elucidate the sugar code
Cells encode information in the sequence of biopolymers, such as nucleic acids, proteins,
and glycans. Although glycans are essential to all living organisms, surprisingly little is …
and glycans. Although glycans are essential to all living organisms, surprisingly little is …
[HTML][HTML] Applications of infrared spectroscopy in polysaccharide structural analysis: Progress, challenge and perspective
T Hong, JY Yin, SP Nie, MY Xie - Food chemistry: X, 2021 - Elsevier
Polysaccharides are important biomacromolecules with numerous beneficial functions and a
wide range of industrial applications. Functions and properties of polysaccharides are …
wide range of industrial applications. Functions and properties of polysaccharides are …
Advances in mass spectrometry‐based glycomics—An update covering the period 2017–2021
The wide variety of chemical properties and biological functions found in proteins is attained
via post‐translational modifications like glycosylation. Covalently bonded to proteins …
via post‐translational modifications like glycosylation. Covalently bonded to proteins …
Toward high-throughput cryogenic IR fingerprinting of mobility-separated glycan isomers
Infrared (IR) spectroscopy is a powerful tool used to infer detailed structural information on
molecules, often in conjunction with quantum-chemical calculations. When applied to …
molecules, often in conjunction with quantum-chemical calculations. When applied to …
Characterization of Elusive Reaction Intermediates Using Infrared Ion Spectroscopy: Application to the Experimental Characterization of Glycosyl Cations
F Braak, H Elferink, KJ Houthuijs… - Accounts of Chemical …, 2022 - ACS Publications
Conspectus A detailed understanding of the reaction mechanism (s) leading to
stereoselective product formation is crucial to understanding and predicting product …
stereoselective product formation is crucial to understanding and predicting product …
Multistage ion mobility spectrometry combined with infrared spectroscopy for glycan analysis
The structural complexity of glycans makes their characterization challenging, not only
because of the presence of various isomeric forms of the precursor molecule but also …
because of the presence of various isomeric forms of the precursor molecule but also …
The combination of laser photodissociation, action spectroscopy, and mass spectrometry to identify and separate isomers
SJP Marlton, AJ Trevitt - Chemical Communications, 2022 - pubs.rsc.org
The separation and detection of isomers remains a challenge for many areas of mass
spectrometry. This article highlights laser photodissociation and ion mobility strategies that …
spectrometry. This article highlights laser photodissociation and ion mobility strategies that …
Gas-phase infrared spectroscopy of glycans and glycoconjugates
K Greis, C Kirschbaum, G von Helden… - Current Opinion in …, 2022 - Elsevier
Glycans are intrinsically complex biomolecules that pose particular analytical challenges.
Standard workflows for glycan analysis are based on mass spectrometry, often coupled with …
Standard workflows for glycan analysis are based on mass spectrometry, often coupled with …
Metal adduction in mass spectrometric analyses of carbohydrates and glycoconjugates
DT Gass, AV Quintero, JB Hatvany… - Mass Spectrometry …, 2024 - Wiley Online Library
Glycans, carbohydrates, and glycoconjugates are involved in many crucial biological
processes, such as disease development, immune responses, and cell–cell recognition …
processes, such as disease development, immune responses, and cell–cell recognition …
Recent advances in high‐resolution traveling wave‐based ion mobility separations coupled to mass spectrometry
Recently, ion mobility spectrometry‐mass spectrometry (IMS‐MS) has become more readily
incorporated into various omics‐based workflows. These growing applications are due to …
incorporated into various omics‐based workflows. These growing applications are due to …