Posttranscriptional modifications of transfer RNAs (tRNAs) are critical for all core aspects of
tRNA function, such as folding, stability, and decoding. Most tRNA modifications were …

Summary tRNA function is based on unique structures that enable mRNA decoding using
anticodon trinucleotides. These structures interact with specific aminoacyl-tRNA synthetases …

Dnmt2 proteins are the most conserved members of the DNA methyltransferase enzyme
family, but their substrate specificity and biological functions have been a subject of …

Transfer RNA (tRNA) have been harbingers of many paradigms in RNA biology. They are
among the first recognized noncoding RNA (ncRNA) playing fundamental roles in RNA …

Post-transcriptional cleavage of RNA molecules to generate smaller fragments is a
widespread mechanism that enlarges the structural and functional complexity of cellular …

Transfer RNA (tRNA)-derived small RNAs (tsRNAs) are among the most ancient small RNAs
in all domains of life and are generated by the cleavage of tRNAs. Emerging studies have …

Transfer RNAs (tRNAs) are abundant small non-coding RNAs that are crucially important for
decoding genetic information. Besides fulfilling canonical roles as adaptor molecules during …

Fungal pathogens threaten ecosystems and human health. Understanding the molecular
basis of their virulence is key to develop new treatment strategies. Here, we characterize …

Wobble uridines (U34) are generally modified in all species. U34 modifications can be
essential in metazoans but are not required for viability in fungi. In this review, we provide an …

RNA 2′, 3′-cyclic phosphate ends play important roles in RNA metabolism as substrates
for RNA ligases during tRNA restriction-repair and tRNA splicing. Diverse bacteria from …