The immunomodulatory and anti-inflammatory role of polyphenols

N Yahfoufi, N Alsadi, M Jambi, C Matar - Nutrients, 2018 - mdpi.com
This review offers a systematic understanding about how polyphenols target multiple
inflammatory components and lead to anti-inflammatory mechanisms. It provides a clear …

Obesity, oxidative stress, adipose tissue dysfunction, and the associated health risks: causes and therapeutic strategies

P Manna, SK Jain - Metabolic syndrome and related disorders, 2015 - liebertpub.com
Obesity is gaining acceptance as a serious primary health burden that impairs the quality of
life because of its associated complications, including diabetes, cardiovascular diseases …

[HTML][HTML] Redox regulation of FoxO transcription factors

LO Klotz, C Sánchez-Ramos, I Prieto-Arroyo… - Redox biology, 2015 - Elsevier
Transcription factors of the forkhead box, class O (FoxO) family are important regulators of
the cellular stress response and promote the cellular antioxidant defense. On one hand …

The role of reactive oxygen species in mesenchymal stem cell adipogenic and osteogenic differentiation: a review

F Atashi, A Modarressi, MS Pepper - Stem cells and development, 2015 - liebertpub.com
Mesenchymal stromal cells (MSCs) are promising candidates for tissue engineering and
regenerative medicine. The multipotent stem cell component of MSC isolates is able to …

Cell models and their application for studying adipogenic differentiation in relation to obesity: a review

FJ Ruiz-Ojeda, AI Rupérez, C Gomez-Llorente… - International journal of …, 2016 - mdpi.com
Over the last several years, the increasing prevalence of obesity has favored an intense
study of adipose tissue biology and the precise mechanisms involved in adipocyte …

[HTML][HTML] European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)

J Egea, I Fabregat, YM Frapart, P Ghezzi, A Görlach… - Redox biology, 2017 - Elsevier
Abstract The European Cooperation in Science and Technology (COST) provides an ideal
framework to establish multi-disciplinary research networks. COST Action BM1203 (EU …

Obesity-associated oxidative stress: strategies finalized to improve redox state

I Savini, MV Catani, D Evangelista, V Gasperi… - International journal of …, 2013 - mdpi.com
Obesity represents a major risk factor for a plethora of severe diseases, including diabetes,
cardiovascular disease, non-alcoholic fatty liver disease, and cancer. It is often …

Effects of oxidative stress on mesenchymal stem cell biology

RA Denu, P Hematti - Oxidative medicine and cellular longevity, 2016 - Wiley Online Library
Mesenchymal stromal/stem cells (MSCs) are multipotent stem cells present in most fetal and
adult tissues. Ex vivo culture‐expanded MSCs are being investigated for tissue repair and …

MSCs vs. iPSCs: Potential in therapeutic applications

K Thanaskody, AS Jusop, GJ Tye… - Frontiers in Cell and …, 2022 - frontiersin.org
Over the past 2 decades, mesenchymal stem cells (MSCs) have attracted a lot of interest as
a unique therapeutic approach for a variety of diseases. MSCs are capable of self-renewal …

Obesogens: a unifying theory for the global rise in obesity

JJ Heindel, RH Lustig, S Howard… - International Journal of …, 2024 - nature.com
Despite varied treatment, mitigation, and prevention efforts, the global prevalence and
severity of obesity continue to worsen. Here we propose a combined model of obesity, a …