Polycystic ovary syndrome and mitochondrial dysfunction

J Zhang, Y Bao, X Zhou, L Zheng - Reproductive Biology and …, 2019 - Springer
Polycystic ovary syndrome (PCOS) is a prevalent hormonal disorder of premenopausal
women worldwide and is characterized by reproductive, endocrine, and metabolic …

[HTML][HTML] Emerging hallmarks of endometriosis metabolism: a promising target for the treatment of endometriosis

J Lu, X Ling, L Liu, A Jiang, C Ren, C Lu… - Biochimica et Biophysica …, 2023 - Elsevier
Endometriosis, characterized by ectopic endometrium growth in the extrauterine
environment, is one of the most notable diseases of the female reproductive system …

Understanding the role of epigenomic, genomic and genetic alterations in the development of endometriosis

H Kobayashi, S Imanaka… - Molecular medicine …, 2014 - spandidos-publications.com
Endometriosis is a complex disease influenced by genetic, epigenetic and environmental
factors. The aim of the present study was to describe genomic instability, genetic …

Mutations in the PTEN tumor gene and risk of endometriosis: a case–control study

S Govatati, VL Kodati, M Deenadayal… - Human …, 2014 - academic.oup.com
STUDY QUESTION Are mutations in the phosphatase and tensin homolog deleted on
chromosome 10 (PTEN) gene associated with endometriosis? SUMMARY ANSWER Loss of …

Genetic, epigenetic and stem cell alterations in endometriosis: new insights and potential therapeutic perspectives

A Forte, M Cipollaro, U Galderisi - Clinical Science, 2014 - portlandpress.com
Human endometrium is a highly dynamic tissue, undergoing periodic growth and regression
at each menstrual cycle. Endometriosis is a frequent chronic pathological status …

Impact of mitochondrial DNA copy number and displacement loop alterations on polycystic ovary syndrome risk in south Indian women

TV Reddy, S Govatati, M Deenadayal, S Sisinthy… - Mitochondrion, 2019 - Elsevier
Sequencing of mitochondrial displacement-loop (D-loop) of polycystic ovary syndrome
(PCOS) patients and (n= 118) and controls (n= 114) of south Indian origin showed …

[HTML][HTML] Endometriosis may be associated with mitochondrial dysfunction in cumulus cells from subjects undergoing in vitro fertilization-intracytoplasmic sperm …

AL Hsu, PM Townsend, S Oehninger, FJ Castora - Fertility and Sterility, 2015 - Elsevier
Objective To determine whether endometriosis is associated with mitochondrial dysfunction
in cumulus (granulosa [GC]) cells of subjects undergoing IVF-intracytoplasmic sperm …

Mitochondrial control region alterations and breast cancer risk: a study in South Indian population

NR Tipirisetti, S Govatati, P Pullari, S Malempati… - PloS one, 2014 - journals.plos.org
Background Mitochondrial displacement loop (D-loop) is the hot spot for mitochondrial DNA
(mtDNA) alterations which influence the generation of cellular reactive oxygen species …

miR-451 Deficiency Is Associated with Altered Endometrial Fibrinogen Alpha Chain Expression and Reduced Endometriotic Implant Establishment in an …

WB Nothnick, A Graham, J Holbert, MJ Weiss - PLoS One, 2014 - journals.plos.org
Endometriosis is defined as the growth of endometrial glandular and stromal components in
ectopic locations and affects as many as 10% of all women of reproductive age. Despite its …

Contribution of cyclin D1 (CCND1) and E-cadherin (CDH1) alterations to colorectal cancer susceptibility: a case–control study

S Govatati, GK Singamsetty, N Nallabelli, S Malempati… - Tumor Biology, 2014 - Springer
Abstract Cyclin D1 (CCND1) and E-cadherin (CDH1) are two important genes of the β-
catenin/LEF pathway that is involved in tumorigenesis of various cancers including …