Chemical design and synthesis of functionalized probes for imaging and treating tumor hypoxia

J Liu, W Bu, J Shi - Chemical reviews, 2017 - ACS Publications
Hypoxia development in tumor is closely associated with its increased aggressiveness and
strong resistance to therapy, leading to the poor prognosis in several cancer types …

A molecular imaging primer: modalities, imaging agents, and applications

ML James, SS Gambhir - Physiological reviews, 2012 - journals.physiology.org
Molecular imaging is revolutionizing the way we study the inner workings of the human
body, diagnose diseases, approach drug design, and assess therapies. The field as a whole …

Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy

WB Dunn, DI Broadhurst, HJ Atherton… - Chemical society …, 2011 - pubs.rsc.org
The study of biological systems in a holistic manner (systems biology) is increasingly being
viewed as a necessity to provide qualitative and quantitative descriptions of the emergent …

Challenges for molecular magnetic resonance imaging

E Terreno, DD Castelli, A Viale, S Aime - Chemical reviews, 2010 - ACS Publications
Challenges for Molecular Magnetic Resonance Imaging | Chemical Reviews ACS ACS
Publications C&EN CAS Find my institution Log In Chemical Reviews ACS Publications. Most …

Molecular imaging of the tumor microenvironment

Z Zhou, ZR Lu - Advanced Drug Delivery Reviews, 2017 - Elsevier
The tumor microenvironment plays a critical role in tumor initiation, progression, metastasis,
and resistance to therapy. It is different from normal tissue in the extracellular matrix …

Chemical exchange saturation transfer (CEST) and MR Z-spectroscopy in vivo: a review of theoretical approaches and methods

M Zaiss, P Bachert - Physics in Medicine & Biology, 2013 - iopscience.iop.org
Chemical exchange saturation transfer (CEST) of metabolite protons that undergo exchange
processes with the abundant water pool enables a specific contrast for magnetic resonance …

Alternatives to gadolinium-based metal chelates for magnetic resonance imaging

S Viswanathan, Z Kovacs, KN Green… - Chemical …, 2010 - ACS Publications
Magnetic resonance imaging (MRI) has been immensely valuable in diagnostic clinical
imaging over the last few decades owing to its exceptional spatial and anatomical …

Nuts and bolts of chemical exchange saturation transfer MRI

G Liu, X Song, KWY Chan… - NMR in Biomedicine, 2013 - Wiley Online Library
Chemical exchange saturation transfer (CEST) has emerged as a novel MRI contrast
mechanism that is well suited for molecular imaging studies. This new mechanism can be …

Molecular magnetic resonance imaging using a redox-active iron complex

H Wang, VC Jordan, IA Ramsay… - Journal of the …, 2019 - ACS Publications
We introduce a redox-active iron complex, Fe-PyC3A, as a biochemically responsive MRI
contrast agent. Switching between Fe3+-PyC3A and Fe2+-PyC3A yields a full order of …

[图书][B] Luminescence of lanthanide ions in coordination compounds and nanomaterials

A de Bettencourt-Dias - 2014 - books.google.com
This comprehensive book presents the theoretical principles, current applications and latest
research developments in the field of luminescent lanthanide complexes; a rapidly …