The clinical significance of 4D printing

A Sheikh, MAS Abourehab, P Kesharwani - Drug Discovery Today, 2023 - Elsevier
Abstract 4D printing is the next step on from 3D printing involving the fourth dimension of
'time'. The programmed 4D-printed objects are capable of changing their shape in response …

[HTML][HTML] Towards 4D printing in pharmaceutics

A Gazzaniga, A Foppoli, M Cerea, L Palugan… - International Journal of …, 2023 - Elsevier
Abstract Four-dimensional printing (4DP) is emerging as an innovative research topic. It
involves the use of smart materials for three-dimensional printing (3DP) of items that change …

Advances in 4D printing: From stimulation to simulation

P Pingale, S Dawre, V Dhapte-Pawar, N Dhas… - Drug Delivery and …, 2023 - Springer
The advancement of four-dimensional (4D) printing has been fueled by the rise in demand
for additive manufacturing and the expansion in shape-memory materials. The printing of …

Shape memory polymeric materials for biomedical applications: an update

D Rokaya, HE Skallevold, V Srimaneepong… - Journal of Composites …, 2023 - mdpi.com
Shape memory polymers (SMPs) are emerging smart materials that have the ability to
change to a shape and revert to their permanent shape on application of external stimulus …

Administration strategies and smart devices for drug release in specific sites of the upper GI tract

M Uboldi, A Melocchi, S Moutaharrik, L Palugan… - Journal of Controlled …, 2022 - Elsevier
Targeting the release of drugs in specific sites of the upper GI tract would meet local
therapeutic goals, improve the bioavailability of specific drugs and help overcoming …

Volumetric additive manufacturing of shape memory polymers

JJ Schwartz, DH Porcincula, CC Cook, EJ Fong… - Polymer …, 2022 - pubs.rsc.org
Shape memory polymers (SMPs) are stimuli responsive materials with programmable
recovery from a deformed state. SMP behavior is often impacted by manufacturing features …

Hydrophilic high drug-loaded 3D printed Gastroretentive system with robust release kinetics

G Mora-Castaño, M Millán-Jiménez, I Caraballo - Pharmaceutics, 2023 - mdpi.com
Three-dimensional printing (3DP) technology enables an important improvement in the
design of new drug delivery systems, such as gastroretentive floating tablets. These systems …

Insights into the safety and versatility of 4D printed intravesical drug delivery systems

M Uboldi, C Perrotta, C Moscheni, S Zecchini, A Napoli… - Pharmaceutics, 2023 - mdpi.com
This paper focuses on recent advancements in the development of 4D printed drug delivery
systems (DDSs) for the intravesical administration of drugs. By coupling the effectiveness of …

Development of a multi-component gastroretentive expandable drug delivery system (GREDDS) for personalized administration of metformin

M Uboldi, A Chiappa, M Rossi… - Expert Opinion on …, 2024 - Taylor & Francis
Objectives Efficacy and compliance of type II diabetes treatment would greatly benefit from
dosage forms providing controlled release of metformin in the upper gastrointestinal tract. In …

Expandable drug delivery systems based on shape memory polymers: Impact of film coating on mechanical properties and release and recovery performance

M Uboldi, C Pasini, S Pandini, F Baldi… - Pharmaceutics, 2022 - mdpi.com
Retentive drug delivery systems (DDSs) are intended for prolonged residence and release
inside hollow muscular organs, to achieve either local or systemic therapeutic goals …