Protein tyrosine kinases (PTKs) are enzymes that transfer phosphate groups to tyrosine
residues on protein substrates. Phosphorylation of proteins causes changes in their function …

Lung cancer is indeed a major cause of cancer‐related deaths worldwide. The development
of tumors involves a complex interplay of genetic, epigenetic, and environmental factors …

GSTP1 belongs to the GSTs family, a group of enzymes involved in detoxification of
exogenous substances and it also plays an important role in cell cycle regulation. Its …

Mesenchymal stromal cells (MSCs) are adult multipotent stem cells residing as pericytes in
various tissues and organs where they can differentiate into specialized cells to replace …

Phosphatase and tensin homolog (Pten) antagonizes PI3K-Akt signaling; therefore, Pten
impairment causes tumorigenesis. However, the correlation between Pten deficiency and …

Arsenic toxicity is a global issue, addressed by the World Health Organization as one of the
major natural calamities faced by humans. More than 137 million individuals in 70 nations …

Breast cancer is the most frequent female malignancy worldwide. Current strategies in
breast cancer therapy, including classical chemotherapy, hormone therapy, and targeted …

Background: Due to the late diagnosis, resulting partly from the absence of national
screening programs, Cervical cancer is a public health concern for women in Sub-Saharan …

Glucocorticoids are widely used to treat B acute lymphoblastic leukemia (B-ALL); however,
the molecular mechanism underlying glucocorticoid response and resistance is unclear. In …

Purpose.: Uveal melanoma is the most common primary intraocular malignancy in adults.
Although local disease can be controlled with radiation therapy or enucleation, many cases …