The treatment of cancer with proton radiation therapy was first suggested in 1946 followed
by the first treatments in the 1950s. As of 2020, almost 200 000 patients have been treated …

Immunotherapy, where the patient's own immune system is exploited to eliminate tumor
cells, has become one of the most prominent new cancer treatment options in the last …

It is well known that radiation therapy causes lymphopenia in patients and that this is
correlated with a negative outcome. The mechanism is not well understood because …

Proton radiotherapy is an advanced treatment option compared with conventional x-ray
treatment, delivering much lower doses of radiation to healthy tissues surrounding the …

Simple Summary The poor survival of unresectable locally advanced stage non-small cell
lung cancer is due to the resistance to chemoradiotherapy and local/distant relapses …

Hepatocellular carcinoma (HCC) is the fifth most common cancer, and its incidence is
rapidly increasing in North America and Western Europe as well as South-East Asia …

Radiotherapy delivered using photons induces an immune response that leads to
modulation of the tumor microenvironment. Clinical studies are ongoing to evaluate immune …

Purpose This phase II study investigated whether durvalumab/tremelimumab with proton
therapy improves the objective response rate (ORR), overall survival (OS), and progression …

Abstract Anti-Programmed cell Death protein 1 (Anti-PD1) or Programmed Death-Ligand 1
(PDL1) immune checkpoint inhibitors provide treatment options for advanced HCC patients …

The combination of radiation therapy (RT) and immunotherapy has emerged as a promising
treatment option in oncology. Historically, x-ray radiation (XRT) has been the most …