The biopsychosocial model of pain dominates the scientific community's understanding of
chronic pain. Indeed, the biopsychosocial approach describes pain and disability as a …

Background Child sexual abuse is considered a modifiable risk factor for mental disorders
across the life course. However the long-term consequences of other forms of child …

Objective This meta-analysis systematically examined the association of reported
psychological trauma and posttraumatic stress disorder (PTSD) with functional somatic …

Findings from three additional centers—Groningen, Netherlands; Mannheim, Germany; and
Sofia, Bulgaria—where cohorts were followed for 14 to 16 years, are reviewed in a third …

Objectives To determine whether epigenetic markers predict dimensional ratings of
depression in maltreated children. Method A genome-wide methylation study was …

Context Many patients presenting for general medical care have a history of sexual abuse.
The literature suggests an association between a history of sexual abuse and somatic …

Child maltreatment is associated with increased risk of an array of mental and physical
health problems. We reviewed studies examining associations of child maltreatment …

Objective We examined the association between retrospective reports of adverse childhood
experiences (ACEs) and painful medical conditions. We also examined the mediating and …

BACKGROUND: Child abuse is highly prevalent and associated with increased risk for a
range of health problems, including cancer, cardiovascular disease, diabetes, psychiatric …

Background. The goal of this investigation was to determine the association between self-
reported childhood trauma and physical disorders among adults in the United States …