Infantile spasms: outcome in clinical studies

R Riikonen - Pediatric neurology, 2020 - Elsevier
Children with infantile spasms are likely to have a poor outcome. Outcome measures for
infantile spasms include primary response to treatment, relapse of spasms, neurological …

Efficacy of treatments for infantile spasms: a systematic review

JM Song, J Hahn, SH Kim… - Clinical …, 2017 - journals.lww.com
Objectives West syndrome (also known as infantile spasm because of its main seizure type)
is a rare form of epilepsy that begins during early infancy. Recent guidelines and reviews on …

Эпилепсия у детей и взрослых женщин и мужчин

ВА Карлов - 2019 - elibrary.ru
В руководстве представлены результаты 60-летней работы автора в области детской
и взрослой неврологии и эпилептологии. Впервые эпилептология представлена в …

Epilepsy syndromes, etiologies, and the use of next‐generation sequencing in epilepsy presenting in the first 2 years of life: a population‐based study

T Stödberg, T Tomson, M Barbaro, H Stranneheim… - …, 2020 - Wiley Online Library
Objective Population‐based data on epilepsy syndromes and etiologies in early onset
epilepsy are scarce. The use of next‐generation sequencing (NGS) has hitherto not been …

Response to second treatment after initial failed treatment in a multicenter prospective infantile spasms cohort

KG Knupp, E Leister, J Coryell, KC Nickels, N Ryan… - …, 2016 - Wiley Online Library
Objective Infantile spasms (IS) represent a severe epileptic encephalopathy presenting in
the first 2 years of life. Recommended first‐line therapies (hormonal therapy or vigabatrin) …

Fifteen years of real‐world data on the use of vigabatrin in individuals with infantile epileptic spasms syndrome

M Kuchenbuch, T Lo Barco, N Chemaly, C Chiron… - …, 2024 - Wiley Online Library
Objective This study was undertaken to evaluate our treatment algorithm for infantile
epileptic spasms syndrome (IESS) used between 2000 and 2018. We initiated vigabatrin …

Antiepileptogenic effects of rapamycin in a model of infantile spasms due to structural lesions

O Akman, SW Briggs, WB Mowrey, SL Moshé… - …, 2021 - Wiley Online Library
Objective Infantile spasms may evolve into persistent epilepsies including Lennox‐Gastaut
syndrome. We compared adult epilepsy outcomes in models of infantile spasms due to …

Pharmacotherapy for seizures in tuberous sclerosis complex

R Nabbout, M Kuchenbuch, C Chiron, P Curatolo - CNS drugs, 2021 - Springer
Epilepsy is one of the main symptoms affecting the lives of individuals with tuberous
sclerosis complex (TSC), causing a high rate of morbidity. Individuals with TSC can present …

Association of time to clinical remission with sustained resolution in children with new-onset infantile spasms

CJ Yuskaitis, JR Mytinger, FM Baumer, B Zhang, S Liu… - Neurology, 2022 - AAN Enterprises
Background and Objectives Standard therapies (adrenocorticotropic hormone [ACTH], oral
steroids, or vigabatrin) fail to control infantile spasms in almost half of children. Early …

Improving outcomes in infantile spasms: role of pharmacotherapy

A Iyer, R Appleton - Pediatric Drugs, 2016 - Springer
Infantile spasms, and specifically within the context of West syndrome, is one of the most
common epileptic encephalopathies to occur in early infancy. Early recognition and …