Wilms tumour

F Spreafico, CV Fernandez, J Brok, K Nakata… - Nature Reviews …, 2021 - nature.com
Wilms tumour (WT) is a childhood embryonal tumour that is paradigmatic of the intersection
between disrupted organogenesis and tumorigenesis. Many WT genes play a critical (non …

[HTML][HTML] Rationale for the treatment of Wilms tumour in the UMBRELLA SIOP–RTSG 2016 protocol

MM Van Den Heuvel-eibrink, JA Hol… - Nature Reviews …, 2017 - nature.com
Abstract The Renal Tumour Study Group of the International Society of Paediatric Oncology
(SIOP–RTSG) has developed a new protocol for the diagnosis and treatment of childhood …

The COVID‐19 pandemic: a rapid global response for children with cancer from SIOP, COG, SIOP‐E, SIOP‐PODC, IPSO, PROS, CCI, and St Jude Global

M Sullivan, E Bouffet… - Pediatric blood & …, 2020 - Wiley Online Library
The COVID‐19 pandemic is one of the most serious global challenges to delivering
affordable and equitable treatment to children with cancer we have witnessed in the last few …

Improving quality and quantity of life for childhood cancer survivors globally in the twenty-first century

MJ Ehrhardt, KR Krull, N Bhakta, Q Liu… - Nature Reviews …, 2023 - nature.com
The contributions of cooperative groups to performing large-cohort clinical trials and long-
term survivorship studies have facilitated advances in treatment, supportive care and …

The genetic changes of Wilms tumour

TD Treger, T Chowdhury, K Pritchard-Jones… - Nature Reviews …, 2019 - nature.com
Wilms tumour is the most common renal malignancy of childhood. The disease is curable in
the majority of cases, albeit at considerable cost in terms of late treatment-related effects in …

Results of the first prospective multi-institutional treatment study in children with bilateral Wilms tumor (AREN0534): a report from the Children's Oncology Group

P Ehrlich, YY Chi, MM Chintagumpala, FA Hoffer… - Annals of …, 2017 - journals.lww.com
Objective: The Children's Oncology Group study AREN0534 aimed to improve event-free
survival (EFS) and overall survival (OS) while preserving renal tissue by intensifying …

New approaches to risk stratification for Wilms tumor

MV Nelson, MM van den Heuvel-Eibrink… - Current opinion in …, 2021 - journals.lww.com
New approaches to risk stratification for Wilms tumor : Current Opinion in Pediatrics New
approaches to risk stratification for Wilms tumor : Current Opinion in Pediatrics Log in or …

Imaging of Wilms tumor: an update

SE Servaes, FA Hoffer, EA Smith, G Khanna - Pediatric radiology, 2019 - Springer
Wilms tumor is the most common pediatric renal tumor, accounting for approximately 7% of
all childhood cancers. Imaging plays an important role in the detection, staging, post-therapy …

Outcome and prognostic factors in stage III favorable-histology Wilms tumor: a report from the Children's Oncology Group Study AREN0532

CV Fernandez, EA Mullen, YY Chi… - Journal of Clinical …, 2018 - ascopubs.org
Background The National Wilms Tumor Study (NWTS) approach to treating stage III
favorable-histology Wilms tumor (FHWT) is Regimen DD4A (vincristine, dactinomycin, and …

PI3K/AKT/mTOR dysregulation and reprogramming metabolic pathways in renal cancer: Crosstalk with the VHL/HIF axis

SC Badoiu, M Greabu, D Miricescu… - International journal of …, 2023 - mdpi.com
Renal cell carcinoma (RCC) represents 85–95% of kidney cancers and is the most frequent
type of renal cancer in adult patients. It accounts for 3% of all cancer cases and is in 7th …