The organic cation transporters (OCTs) OCT1, OCT2, OCT3, novel OCT (OCTN) 1, OCTN2,
multidrug and toxin exclusion (MATE) 1, and MATE kidney-specific 2 are polyspecific …

This article reviews what is presently known about the biological roles of the diet-derived
compound ergothioneine (ET). ET seems important to humans because it is rapidly taken up …

There has been a recent surge of interest in the unique low molecular weight dietary
thiol/thione, ergothioneine. This compound can accumulate at high levels in the body from …

In all vertebrates including mammals, the ergothioneine transporter ETT (obsolete name
OCTN1; human gene symbol SLC22A4) is a powerful and highly specific transporter for the …

L-Ergothioneine (EGT) is a natural antioxidant derived from microorganisms, especially in
edible mushrooms. EGT is found to be highly accumulated in tissues that are susceptible to …

The carnitine/organic cation transporter (OCTN) family consists of three transporter isoforms,
ie OCTN1 (SLC22A4) and OCTN2 (SLC22A5) in humans and animals and Octn3 …

Individual cells and epithelia control the chemical exchange with the surrounding
environment by the fine-tuned expression, localization, and function of an array of …

OCTN is a small subfamily of membrane transport proteins that belongs to the larger SLC22
family. Two of the three members of the subfamily, namely, OCTN2 and OCTN1, are present …

The relationships between depression and gut microbiota, particularly those involving the
immune system, have become a major focus of recent research. Here, we analyzed changes …

Background Clinically used antidepressants suffer from various side effects. Therefore, we
searched for a safe antidepressant with minimal side effects among food ingredients that are …