Large-Artery Stiffness in Health and Disease: JACC State-of-the-Art Review

JA Chirinos, P Segers, T Hughes… - Journal of the American …, 2019 - jacc.org
A healthy aorta exerts a powerful cushioning function, which limits arterial pulsatility and
protects the microvasculature from potentially harmful fluctuations in pressure and blood …

Pulsatile arterial haemodynamics in heart failure

T Weber, JA Chirinos - European heart journal, 2018 - academic.oup.com
Due to the cyclic function of the human heart, pressure and flow in the circulation are
pulsatile rather than continuous. Addressing pulsatile haemodynamics starts with the most …

The role of ventricular–arterial coupling in cardiac disease and heart failure: assessment, clinical implications and therapeutic interventions. A consensus document of …

I Ikonomidis, V Aboyans, J Blacher… - European journal of …, 2019 - Wiley Online Library
Ventricular–arterial coupling (VAC) plays a major role in the physiology of cardiac and aortic
mechanics, as well as in the pathophysiology of cardiac disease. VAC assessment …

Prospective evaluation of cardiovascular risk 10 years after a hypertensive disorder of pregnancy

LD Levine, B Ky, JA Chirinos, J Koshinksi… - Journal of the American …, 2022 - jacc.org
Background Hypertensive disorders of pregnancy (HDP) are associated with increased risk
of cardiovascular disease (CVD) 20-30 years later; however, cardiovascular (CV) risk in the …

Estrogen-mediated gaseous signaling molecules in cardiovascular disease

J Teoh, X Li, T Simoncini, D Zhu, X Fu - Trends in Endocrinology & …, 2020 - cell.com
Gender difference is well recognized as a key risk factor for cardiovascular disease (CVD).
Estrogen, the primary female sex hormone, improves cardiovascular functions through …

Systemic hypertension at high altitude

O Narvaez-Guerra, K Herrera-Enriquez… - …, 2018 - Am Heart Assoc
568 Hypertension September 2018 prevalence of hypertension with a 2% increase for
every≈ 100 m (≈ 330 ft)-increase in altitude above 3000 mASL (≈ 9800 ft). 16 …

Dietary nitrate and population health: a narrative review of the translational potential of existing laboratory studies

OM Shannon, C Easton, AI Shepherd, M Siervo… - BMC Sports Science …, 2021 - Springer
Background Dietary inorganic nitrate (NO3−) is a polyatomic ion, which is present in large
quantities in green leafy vegetables and beetroot, and has attracted considerable attention …

C-reactive protein, interleukin-6, trimethylamine-N-oxide, syndecan-1, nitric oxide, and tumor necrosis factor receptor-1 in heart failure with preserved versus reduced …

XY Gui, SW Rabkin - Current Heart Failure Reports, 2023 - Springer
Abstract Purpose of Review The purpose of this review was to synthesize the evidence on
non-traditional biomarkers from proteomic and metabolomic studies that may distinguish …

Personalized physiologic flow waveforms improve wave reflection estimates compared to triangular flow waveforms in adults

N Shenouda, JM Stock, JC Patik… - American Journal …, 2021 - journals.physiology.org
Central aortic pressure waveforms contain valuable prognostic information in addition to
central systolic pressure. Using pressure-flow relations, wave separation analysis can be …

Effect of acute handgrip and aerobic exercise on wasted pressure effort and arterial wave reflections in healthy aging

JM Stock, N Shenouda… - American Journal …, 2023 - journals.physiology.org
Aging increases arterial stiffness and wave reflections that augment left ventricular wasted
pressure effort (WPE). A single bout of exercise may be effective at acutely reducing WPE …