Cell penetrating peptides: The potent multi-cargo intracellular carriers
ABSTRACT Introduction: Cell penetrating peptides (CPPs) known as protein translocation
domains (PTD), membrane translocating sequences (MTS), or Trojan peptides (TP) are able …
domains (PTD), membrane translocating sequences (MTS), or Trojan peptides (TP) are able …
The role of microRNA in the inflammatory response of wound healing
Y Jiang, X Xu, L Xiao, L Wang, S Qiang - Frontiers in Immunology, 2022 - frontiersin.org
Wound healing, a highly complex pathophysiological response to injury, includes four
overlapping phases of hemostasis, inflammation, proliferation, and remodeling. Initiation …
overlapping phases of hemostasis, inflammation, proliferation, and remodeling. Initiation …
Emerging insights of peptide-based nanotherapeutics for effective management of rheumatoid arthritis
Rheumatoid arthritis (RA) is a chronic, prevalent, immune-mediated, inflammatory, joint
disorder affecting millions of people worldwide. Despite current treatment options, many …
disorder affecting millions of people worldwide. Despite current treatment options, many …
Lauric acid ameliorates lipopolysaccharide (LPS)-induced liver inflammation by mediating TLR4/MyD88 pathway in Sprague Dawley (SD) rats
Background Lipopolysaccharide (LPS) is an endotoxin that leads to inflammation in many
organs, including liver. It binds to pattern recognition receptors, that generally recognise …
organs, including liver. It binds to pattern recognition receptors, that generally recognise …
Activation of Kupffer cells in NAFLD and NASH: Mechanisms and therapeutic interventions
GX Xu, S Wei, C Yu, SQ Zhao, WJ Yang… - Frontiers in Cell and …, 2023 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are
emerging as the leading causes of liver disease worldwide. These conditions can lead to …
emerging as the leading causes of liver disease worldwide. These conditions can lead to …
TLR9: a friend or a foe
The innate immune system is a primary protective line in our body. It confers its protection
through different pattern recognition receptors (PRRs), especially toll like receptors (TLRs) …
through different pattern recognition receptors (PRRs), especially toll like receptors (TLRs) …
Partial replacement of dietary fat with krill oil or coconut oil alleviates dyslipidemia by partly modulating lipid metabolism in lipopolysaccharide-injected rats on a high …
HK Son, BH Kim, J Lee, S Park, CB Oh, S Jung… - International Journal of …, 2022 - mdpi.com
This study investigated the effects of partial replacement of dietary fat with krill oil (KO) or
coconut oil (CO) on dyslipidemia and lipid metabolism in rats fed with a high-fat diet (HFD) …
coconut oil (CO) on dyslipidemia and lipid metabolism in rats fed with a high-fat diet (HFD) …
Toll-like receptor signaling inhibitory peptide improves inflammation in animal model and human systemic lupus erythematosus
WY Baek, YS Choi, SW Lee, IO Son, KW Jeon… - International Journal of …, 2021 - mdpi.com
Toll-like receptors (TLRs) play a major role in the innate immune system. Several studies
have shown the regulatory effects of TLR-mediated pathways on immune and inflammatory …
have shown the regulatory effects of TLR-mediated pathways on immune and inflammatory …
A peptide derived from the core β-sheet region of TIRAP decoys TLR4 and reduces inflammatory and autoimmune symptoms in murine models
Background TLRs are some of the actively pursued drug-targets in immune disorders.
Owing to a recent surge in the cognizance of TLR structural biology and signalling …
Owing to a recent surge in the cognizance of TLR structural biology and signalling …
Electroacupuncture Alleviates Pain Responses and Inflammation in Collagen‐Induced Arthritis Rats via Suppressing the TLR2/4‐MyD88‐NF‐κB Signaling Pathway
SY Sun, QQ Yan, LN Qiao, YN Shi… - Evidence‐Based …, 2023 - Wiley Online Library
Background and Purpose. Electroacupuncture (EA) is effective on rheumatoid arthritis (RA),
an autoimmune disease, but the mechanisms involved remain poorly understood. This study …
an autoimmune disease, but the mechanisms involved remain poorly understood. This study …