Motion and uncertainty in radiotherapy is traditionally handled via margins. The clinical
target volume (CTV) is expanded to a larger planning target volume (PTV), which is …

Background: Deformable image registration (DIR) is increasingly used in the field of
radiation therapy (RT) to account for anatomical deformations. The aims of this paper are to …

External beam radiotherapy is extensively used to treat cervical carcinomas. A single
planning CT scan enables the calculation of the dose distribution. The treatment is delivered …

The aim of this study is to develop an anatomical robust optimization method for intensity-
modulated proton therapy (IMPT) that accounts for interfraction variations in nasal cavity …

Purpose To characterize daily geometrical variations of gastrointestinal organs with respect
to pancreatic tumors, through a population-based statistical model. Materials and methods …

Intensity modulated radiation therapy (IMRT) has become standard of care for most cancer
sites that are managed by radiation therapy. This book documents the evolution of this …

Radiotherapy (RT) requires meticulous planning prior to treatment, where the RT plan is
optimized with organ delineations on a pre-treatment Computed Tomography (CT) scan of …

Background This study compared adaptive replanning and repositioning corrections based
on soft-tissue matching for prostate cancer by using the magnetic resonance-guided …

Background. The bladder is a tumour site well suited for adaptive radiotherapy (ART) due to
large inter-fractional changes, but it also displays considerable intra-fractional motion. The …

Objective. The accuracy of radiotherapy for patients with locally advanced cancer is
compromised by independent motion of multiple targets. To date, MLC tracking approaches …