[图书][B] Epilepsy: a public health imperative

World Health Organization - 2019 - apps.who.int
Epilepsy is a brain disease characterized by abnormal electrical activity causing seizures or
unusual behaviour, sensations and sometimes loss of awareness. It carries neurological …

[HTML][HTML] Recent advances in neuroimaging of epilepsy

AM Goodman, JP Szaflarski - Neurotherapeutics, 2021 - Elsevier
Human neuroimaging has had a major impact on the biological understanding of epilepsy
and the relationship between pathophysiology, seizure management, and outcomes. This …

Facial emotion processing in patients with seizure disorders

JP Szaflarski, JB Allendorfer, R Nenert… - Epilepsy & Behavior, 2018 - Elsevier
Studies of emotion processing are needed to better understand the pathophysiology of
psychogenic nonepileptic seizures (PNES). We examined the differences in facial emotion …

Spectrum and time course of epilepsy and the associated cognitive decline in MECP2 duplication syndrome

D Marafi, B Suter, R Schultz, D Glaze, VN Pavlik… - Neurology, 2019 - AAN Enterprises
Objective We characterized the epilepsy features and contribution to cognitive regression in
47 patients with MECP2 duplication syndrome (MDS) and reviewed these characteristics in …

A pilot study of combined endurance and resistance exercise rehabilitation for verbal memory and functional connectivity improvement in epilepsy

JB Allendorfer, GA Brokamp, R Nenert, JP Szaflarski… - Epilepsy & Behavior, 2019 - Elsevier
Memory impairment is common in persons with epilepsy (PWE), and exercise may be a
strategy for its improvement. In this pilot study, we hypothesized that exercise rehabilitation …

Antiepileptogenesis and disease modification: Progress, challenges, and the path forward—Report of the Preclinical Working Group of the 2018 NINDS‐sponsored …

AS Galanopoulou, W Löscher, L Lubbers… - Epilepsia …, 2021 - Wiley Online Library
Epilepsy is one of the most common chronic brain diseases and is often associated with
cognitive, behavioral, or other medical conditions. The need for therapies that would …

Epilepsy benchmarks area IV: Limit or prevent adverse consequence of seizures and their treatment across the life span

JE Jones, MR Asato, MG Brown, JL Doss… - Epilepsy …, 2020 - journals.sagepub.com
Epilepsy represents a complex spectrum disorder, with patients sharing seizures as a
common symptom and manifesting a broad array of additional clinical phenotypes. To …

Altered fronto-limbic-motor response to stress differs between functional and epileptic seizures in a TBI model

AM Goodman, JB Allendorfer, GC Taylor, NS Philip… - Epilepsy & Behavior, 2024 - Elsevier
Abstract Background and Objectives Psychogenic nonepileptic (functional) seizures (FS)
clinically resemble epileptic seizures (ES) with both often preceded by traumatic brain injury …

Preclinical development of an EP2 antagonist for post-seizure cognitive deficits

NH Varvel, R Amaradhi, C Espinosa-Garcia, S Duddy… - …, 2023 - Elsevier
Cognitive comorbidities can substantially reduce quality of life in people with epilepsy.
Inflammation is a component of all chronic diseases including epilepsy, as well as acute …

Diagnostic delay in functional seizures is associated with abnormal processing of facial emotions

JP Szaflarski, JB Allendorfer, AM Goodman… - Epilepsy & Behavior, 2022 - Elsevier
Purpose In patients with functional seizures (FS), delay in diagnosis (DD) may negatively
affect outcomes. Altered brain responses to emotional stimuli have been shown in adults …