Atrial fibrillation (AF) is of public health importance and profoundly increases morbidity,
mortality, and healthrelated expenditures. Morbidities include the increased risks of …

While management of atrial fibrillation (AF) patients is improved by guideline-conform
application of anticoagulant therapy, rate control, rhythm control, and therapy of …

Atrial fibrillation is a highly prevalent arrhythmia and a major risk factor for stroke, heart
failure and death. We conducted a genome-wide association study (GWAS) in individuals of …

Atrial fibrillation (AF) is the most common sustained arrhythmia. Previous studies have
identified several genetic loci associated with typical AF. We sought to identify common …

We expanded our genome-wide association study on atrial fibrillation (AF) in Iceland, which
previously identified risk variants on 4q25, and tested the most significant associations in …

Background—Intergenic variations on chromosome 4q25, close to the PITX2 transcription
factor gene, are associated with atrial fibrillation (AF). We therefore tested whether adult …

Atrial fibrillation (AF), the most prevalent sustained cardiac arrhythmia, often coexists with
the related arrhythmia atrial flutter (AFL). Limitations in effectiveness and safety of current …

Background—Pitx2 is a homeobox transcription factor that plays a pivotal role in early
left/right determination during embryonic development. Pitx2 loss-of-function mouse mutants …

Atrial fibrillation (AF) is known to be the most common supraventricular arrhythmia affecting
up to 1% of the general population. Its prevalence exponentially increases with age and …

Objectives: This study tested the hypothesis that chromosome 4q25 single-nucleotide
polymorphisms (SNPs) associate with atrial fibrillation (AF) recurrence after catheter …