Here we present a protocol for the construction and use of two types of nanocarrier based on
bacterial membrane materials for cancer vaccine delivery. Cancer vaccines induce tumor …

Therapies modulating the immune system offer the prospect of treating a wide range of
conditions including infectious diseases, cancer and autoimmunity. Biomaterials can …

Nanoparticle (NP)-based mRNA cancer vaccines hold great promise to realize personalized
cancer treatments. To advance this technology requires delivery formulations for efficient …

Covalent organic frameworks (COFs) are porous organic polymeric materials that are
composed of organic elements and linked together by the thermodynamically stable …

Taking advantage of the excellent trans-cleavage activity, CRISPR-based diagnostics
(CRISPR-Dx) has shown great promise in molecular diagnostics. However, the single …

Immunotherapy holds great promise for the treatment of aggressive and metastatic cancers;
however, currently available immunotherapeutics, such as immune checkpoint blockade …

Inducing pyroptosis in cancer cells holds great potential in cancer immunotherapy.
Lipopolysaccharide (LPS)-sensing noncanonical pathways are an important mechanism of …

In addition to the contribution of cancer cells, the solid tumor microenvironment (TME) has a
critical role in determining tumor expansion, antitumor immunity, and the response to …

The conception, synthesis, and invention of a nanostructure, now known as the spherical
nucleic acid, or SNA, in 1996 marked the advent of a new field of chemistry. Over the past …

Whole tumor cell-based vaccines include all potential antigen-rich cell lysates to target a
specific type of tumor without the need to find the best antigen candidate in protein-or …