[HTML][HTML] Natural products in non-alcoholic fatty liver disease (NAFLD): Novel lead discovery for drug development
L Wang, Y Yan, L Wu, J Peng - Pharmacological Research, 2023 - Elsevier
With changing lifestyles, non-alcoholic fatty liver disease (NAFLD) has become the most
prevalent liver disease worldwide. A substantial increase in the incidence, mortality, and …
prevalent liver disease worldwide. A substantial increase in the incidence, mortality, and …
[HTML][HTML] Berberine: An inspiring resource for the treatment of colorectal diseases
F Cao, W Xia, S Dai, C Wang, R Shi, Y Yang… - Biomedicine & …, 2023 - Elsevier
Colorectal cancer is a prevalent malignant tumor with a complex and diverse pathogenesis.
In recent years, natural products have shown promising application prospects as sources of …
In recent years, natural products have shown promising application prospects as sources of …
Berberine Induces Mitophagy through Adenosine Monophosphate-Activated Protein Kinase and Ameliorates Mitochondrial Dysfunction in PINK1 Knockout Mouse …
JH Um, KM Lee, YY Kim, DY Lee, E Kim… - International Journal of …, 2023 - mdpi.com
Mitophagy stimulation has been shown to have a therapeutic effect on various
neurodegenerative diseases. However, nontoxic mitophagy inducers are still very limited. In …
neurodegenerative diseases. However, nontoxic mitophagy inducers are still very limited. In …
[HTML][HTML] Network Pharmacology Combined with Experimental Validation to Investigate the Mechanism of the Anti-Hyperuricemia Action of Portulaca oleracea Extract
Y Zhang, S Zhu, Y Gu, Y Feng, B Gao - Nutrients, 2024 - mdpi.com
Background/Objectives: Hyperuricemia (HUA) is a common metabolic disease caused by
purine metabolic disorders in the body. Portulaca oleracea L.(PO) is an edible wild …
purine metabolic disorders in the body. Portulaca oleracea L.(PO) is an edible wild …
Preparation and Evaluation of Berberine-Excipient Complexes in Enhancing the Dissolution Rate of Berberine Incorporated into Pellet Formulations
M Abbaspour, F Faeznia, P Zanjanian, M Ruzbehi… - AAPS …, 2024 - Springer
Berberine is used in the treatment of metabolic syndrome and its low solubility and very poor
oral bioavailability of berberine was one of the primary hurdles for its market approval. This …
oral bioavailability of berberine was one of the primary hurdles for its market approval. This …
Effect of Berberine Phytosome on reproductive, dermatologic, and metabolic characteristics in women with polycystic ovary syndrome: a controlled, randomized, multi …
F Di Pierro, R Sultana, AZ Eusaph, S Abrar… - Frontiers in …, 2023 - frontiersin.org
Background: Berberine is a poorly absorbed natural alkaloid widely used as nutraceutical to
counteract diarrhoea and to lower cholesterol and hyperglycaemia. It has also been …
counteract diarrhoea and to lower cholesterol and hyperglycaemia. It has also been …
Protective Effects of Berberine on Nonalcoholic Fatty Liver Disease in db/db Mice via AMPK/SIRT1 Pathway Activation
C Chen, X Liu, B Deng - Current Medical Science, 2024 - Springer
Objective Berberine (BBR) has emerged as a promising therapeutic agent for nonalcoholic
fatty liver disease (NAFLD). This study aims to elucidate the underlying molecular …
fatty liver disease (NAFLD). This study aims to elucidate the underlying molecular …
[HTML][HTML] Chemical nature of metabolic activation of natural products in traditional Chinese medicines possibly associated with toxicities
Y Liu, X Wang, M Liu, X Hao, Y Peng… - Acupuncture and Herbal …, 2024 - journals.lww.com
Ensuring the safety of traditional Chinese medicines (TCM) has perennially presented a
universal challenge in the healthcare realm. Meticulous investigations into the toxicological …
universal challenge in the healthcare realm. Meticulous investigations into the toxicological …
Inhibition of Macrophage Pyroptosis─ A New Therapeutic Strategy to Alleviate T-2 Toxin-Induced Subacute Liver Injury by Directly Competing with the Key Target
X Xu, Y Wu, Y Zhao, A Liu, C Yi, A Zhang… - Journal of Agricultural …, 2024 - ACS Publications
Multiple compounds are related to the development of liver injury, such as toxins, drugs, and
environmental pollutants. Although there are reports that the T-2 toxin can cause liver injury …
environmental pollutants. Although there are reports that the T-2 toxin can cause liver injury …
Berberine hydrochloride delays citrus sour rot mainly by disrupting carbohydrate and energy metabolism of Geotrichum citri-aurantii spores
L Li, B Lin, Y Ting, M Li, J Hu, J Song, Y Yan… - Pesticide Biochemistry …, 2024 - Elsevier
Citrus sour rot is a common postharvest citrus disease caused by Geotrichum citri-aurantiiti,
which has led to enormous economic losses, particularly during rainy seasons. In this study …
which has led to enormous economic losses, particularly during rainy seasons. In this study …