Cell plasticity and prostate cancer: The role of epithelial–mesenchymal transition in tumor progression, invasion, metastasis and cancer therapy resistance

S Papanikolaou, A Vourda, S Syggelos, K Gyftopoulos - Cancers, 2021 - mdpi.com
Simple Summary Although epithelial-to-mesenchymal transition (EMT) is a well-known
cellular process involved during normal embryogenesis and wound healing, it also has a …

Neuroendocrine factors and head and neck squamous cell carcinoma: An affair to remember

I Solomon, VM Voiculescu, C Caruntu, M Lupu… - Disease …, 2018 - Wiley Online Library
Head and neck squamous cell carcinoma (HNSCC) is one of the most aggressive
malignancies. Therefore, the major goal of cancer treatment is inhibition of tumor cell growth …

Allicin could potentially alleviate oral cancer pain by inhibiting “pain mediators” TNF-alpha, IL-8, and endothelin

AH Alamir, S Patil - Current Issues in Molecular Biology, 2021 - mdpi.com
To evaluate the effects of allicin on mediators of pain secreted by oral cancer cells in vitro,
single-cell suspensions were prepared by enzymatic method from oral squamous cell …

[HTML][HTML] Endothelin-converting enzyme-1 in cancer aggressiveness

JC Tapia, I Niechi - Cancer Letters, 2019 - Elsevier
Abstract The endothelin-1 (ET-1) axis contributes to the pathophysiology of several cancers
by promoting tumor development and progression. This peptide is activated from its …

Nitrative stress, oxidative stress and plasma endothelin levels after inhalation of particulate matter and ozone

P Kumarathasan, E Blais, A Saravanamuthu… - Particle and fibre …, 2015 - Springer
Background While exposure to ambient air contaminants is clearly associated with adverse
health outcomes, disentangling mechanisms of pollutant interactions remains a challenge …

Blockade of endothelin receptors reduces tumor-induced ongoing pain and evoked hypersensitivity in a rat model of facial carcinoma induced pain

CM Kopruszinski, RC Dos Reis, E Gambeta… - European Journal of …, 2018 - Elsevier
Pain reported by patients with head and neck cancer is characterized as persistent pain with
mechanical allodynia. Pain management is inadequate for many patients, highlighting the …

Cisplatin suppresses proliferation, migration and invasion of nasopharyngeal carcinoma cells in vitro by repressing the Wnt/β-catenin/Endothelin-1 axis via activating …

P Yin, G Song, Z Jiang - Cancer Chemotherapy and Pharmacology, 2018 - Springer
Purpose Nasopharyngeal carcinoma (NPC) is one of the most commonly diagnosed
cancers worldwide with significantly high prevalence in Southern China. Chemoprevention …

Modulation of the endothelin system in colorectal cancer liver metastasis: influence of epigenetic mechanisms?

MR Mahdi, RB Georges, DM Ali, RF Bedeer… - Frontiers in …, 2020 - frontiersin.org
Targeting of endothelin system genes is a promising strategy in cancer therapy. The
modulation of these genes was explored in a model of colorectal cancer (CRC) liver …

Pain biomarkers in cancer: an overview

F Calapai, E Mondello, C Mannucci… - Current …, 2021 - ingentaconnect.com
Background: Pain is a common symptom in oncologic patients and its management is
generally guided with reference to pain individually perceived by patients and expressed …

Endocan, ET-1, and etar expression profiles in unicystic ameloblastoma, multicystic ameloblastoma, and ameloblastic carcinoma

S Irani, Z Mohsenifar - Middle East Journal of Cancer, 2019 - mejc.sums.ac.ir
Background: Odontogenic lesions range from simple cysts to benign tumors and
carcinomas. Unicystic ameloblastoma is a monocystic lesion and a less aggressive tumor …