Microwave-assisted multicomponent reactions in heterocyclic chemistry and mechanistic aspects

S Gulati, SE John… - Beilstein Journal of Organic …, 2021 - beilstein-journals.org
Microwave-assisted (MWA) multicomponent reactions (MCRs) have successfully emerged
as one of the useful tools in the synthesis of biologically relevant heterocycles. These …

Synthesis and pharmacophore modeling of naphthoquinone derivatives with cytotoxic activity in human promyelocytic leukemia HL-60 cell line

E Pérez-Sacau, RG Díaz-Peñate… - Journal of medicinal …, 2007 - ACS Publications
Catalyst/HypoGen pharmacophore modeling approach and three-dimensional quantitative
structure− activity relationship (3D-QSAR)/comparative molecular similarity indices analysis …

Multicomponent Synthesis of Poly-Substituted Benzo[a]pyrano[2,3-c]phenazine Derivatives under Microwave Heating

SL Wang, FY Wu, C Cheng, G Zhang… - ACS Combinatorial …, 2011 - ACS Publications
A new one-pot two-step tandem synthesis of highly functionalized benzo [a] pyrano [2, 3-c]
phenazine derivatives via microwave-assisted multicomponent reactions of 2 …

Progress in quinoxaline synthesis (Part 2)

VA Mamedov, NA Zhukova - Progress in heterocyclic chemistry, 2013 - Elsevier
In the second part of this two-part review (for Part 1 see VA Mamedov, A. Nataliya, NA
Zhukova, Prog. Heterocycl. Chem. 2012, 24, 55), recent advances in the synthesis of …

Design and synthesis of a novel series of pyranonaphthoquinones as topoisomerase II catalytic inhibitors

S Jiménez-Alonso, HC Orellana… - Journal of medicinal …, 2008 - ACS Publications
On the basis of previous pharmacophore modeling studies of naphthoquinones derivatives,
we have designed and synthesized a new set of pyranonaphthoquinones. These …

The chemistry and applications of the quinoxaline compounds

M Soleymani, M Chegeni - Current Organic Chemistry, 2019 - ingentaconnect.com
The quinoxaline derivatives are beneficial compounds because of their various medicinal
and industrial applications. They are well-known for application in organic light emitting …

Quinoxaline macrocycles

VA Mamedov, AA Kalinin - Advances in Heterocyclic Chemistry, 2014 - Elsevier
Macrocyclic cоmpounds are some of the most interesting objects in modern synthetic
chemistry and, as shown in this critical review, they provide an attractive entry into …

Synthesis, antitumor activity, and structure-activity relationship of some benzo [a] pyrano [2, 3-c] phenazine derivatives

J Gao, M Chen, X Tong, H Zhu, H Yan… - … Chemistry & High …, 2015 - ingentaconnect.com
A series of benzo [a] pyrano [2, 3-c] phenazine derivatives with a wide range of substitutions
at ring C of the benzophenazine were designed and synthesized using the one-pot, four …

Double domino Knoevenagel hetero Diels–Alder strategy towards bis-pyrano-1, 4-benzoquinones

S Jimenez-Alonso, A Estevez-Braun, AG Ravelo… - Tetrahedron, 2007 - Elsevier
Several bis-pyrano-l, 4-benzoquinones have been synthesized by a double domino
Knoevenagel hetero Diels–Alder reaction. The synthetic approach is highly efficient allowing …

Isocyanide-based four-component synthesis of benzo [a] pyrano [2, 3-c] phenazines

T Amanpour, P Mirzaei, A Bazgir - Synthesis, 2012 - thieme-connect.com
An efficient and simple method for the synthesis of biologically interesting benzo [a] pyrano
[2, 3-c] phenazines by a four-component reaction of o-phenylenediamines, 2 …