Potent acetylcholinesterase inhibitors: potential drugs for Alzheimer's disease
H Akıncıoğlu, İ Gülçin - Mini reviews in medicinal chemistry, 2020 - ingentaconnect.com
Alzheimer's disease (AD) is one of the cognitive or memory-related impairments occurring
with advancing age. Since its exact mechanism is not known, the full therapy has still not …
with advancing age. Since its exact mechanism is not known, the full therapy has still not …
Sulfonamide inhibitors: a patent review 2013-present
İ Gulçin, P Taslimi - Expert opinion on therapeutic patents, 2018 - Taylor & Francis
Introduction: Sulfonamide compounds are significant class of synthetic bacteriostatic
antibiotics still which used today for the therapy of bacterial infections and those caused by …
antibiotics still which used today for the therapy of bacterial infections and those caused by …
Discovery of sulfadrug–pyrrole conjugates as carbonic anhydrase and acetylcholinesterase inhibitors
Human carbonic anhydrase (hCA) isoenzymes are zinc ion‐containing, widespread
metalloenzymes and they classically play a role in pH homeostasis maintenance. CA …
metalloenzymes and they classically play a role in pH homeostasis maintenance. CA …
Comprehensive Metabolite Profiling of Cinnamon (Cinnamomum zeylanicum) Leaf Oil Using LC-HR/MS, GC/MS, and GC-FID: Determination of Antiglaucoma …
In this study, for the first time, the antioxidant and antidiabetic properties of the essential oil
from cinnamon (Cinnamomum zeylanicum) leaves were evaluated and investigated using …
from cinnamon (Cinnamomum zeylanicum) leaves were evaluated and investigated using …
Synthesis and biological evaluation of novel tris-chalcones as potent carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase and α-glycosidase inhibitors
S Burmaoglu, AO Yilmaz, MF Polat, R Kaya, İ Gulcin… - Bioorganic …, 2019 - Elsevier
A novel class of fluoro-substituted tris-chalcones derivatives (5a-5i) was synthesized from
phloroglucinol and corresponding benzaldehydes. A three step synthesis method was …
phloroglucinol and corresponding benzaldehydes. A three step synthesis method was …
LC–MS/MS analysis, antioxidant and anticholinergic properties of galanga (Alpinia officinarum Hance) rhizomes
Abstract Galanga (Alpinia officinarum Hance) is a pungent and aromatic rhizome, which is a
member of the ginger family (Zingiberaceae). The rhizomes of this plant have been used as …
member of the ginger family (Zingiberaceae). The rhizomes of this plant have been used as …
Isofraxidin: Antioxidant, Anti‐carbonic Anhydrase, Anti‐cholinesterase, Anti‐diabetic, and in Silico Properties
The development of innovative pharmacological formulations for the treatment and
prevention of various major diseases, including cancer, diabetes, and glaucoma, has been …
prevention of various major diseases, including cancer, diabetes, and glaucoma, has been …
Rosmarinic acid inhibits some metabolic enzymes including glutathione S-transferase, lactoperoxidase, acetylcholinesterase, butyrylcholinesterase and carbonic …
Rosmarinic acid (RA) is a natural polyphenol contained in many aromatic plants with
promising biological activities. Carbonic anhydrases (CAs, EC 4.2. 1.1) are widespread and …
promising biological activities. Carbonic anhydrases (CAs, EC 4.2. 1.1) are widespread and …
Investigation of inhibitory properties of some hydrazone compounds on hCA I, hCA II and AChE enzymes
Recently, inhibition of carbonic anhydrase (hCA) and acetylcholinesterase (AChE) have
appeared as a promising approach for pharmacological intervention in a variety of disorders …
appeared as a promising approach for pharmacological intervention in a variety of disorders …
Antioxidant and acetylcholinesterase inhibition properties of novel bromophenol derivatives
In this study, series of novel bromophenol derivatives were synthesized and investigated for
their antioxidant and AChE inhibition properties. Novel brominated diarylmethanones were …
their antioxidant and AChE inhibition properties. Novel brominated diarylmethanones were …