Heme (iron-protoporphyrin IX) is an essential co-factor involved in several biological
processes, including neuronal survival and differentiation. Nevertheless, an excess of free …

A host of human diseases, including Parkinson's disease and Dementia with Lewy bodies,
are suspected to be directly linked to protein aggregation. Amyloid protein aggregates and …

Protein misfolding and aggregation have been associated with several human diseases
such as Alzheimer's, Parkinson's and familial amyloid polyneuropathy etc. In this study, anti …

In this work, we developed β-lactoglobulin nanofibrils by alkaline-thermal activation methods
for Pb removal. The protein fibrils exhibited effective adsorption and selectivity for lead (II) …

Iron accumulation in substantia nigra pars compacta (SNpc) has been proved to be a
prominent pathophysiological feature of Parkinson's diseases (PD), which can induce the …

Human calcitonin (hCT) is an endogenous polypeptide commonly employed in treating
bone resorption-related illnesses, but its clinical application is limited due to its high …

Parkinson's Disease (PD) is a neurodegenerative disease for which there currently is no
cure. Aggregation of the pre-synaptic protein α-synuclein (aSN) into oligomers (αSOs) is …

Parkinson's disease is a yet incurable, age‐related neurodegenerative disorder
characterized by the aggregation of small neuronal protein α‐synuclein into amyloid fibrils …

Mitochondrial dysfunction has achieved an increasing interest in the field of
neurodegeneration as a pathological hallmark for different disorders. The impact of …

The fibrillation pathway of alpha-Synuclein, the causative protein of Parkinson's disease,
encompasses transient, heterogeneous oligomeric forms whose structural understanding …