Spinal interneurons as gatekeepers to neuroplasticity after injury or disease

LV Zholudeva, VE Abraira… - Journal of …, 2021 - Soc Neuroscience
Spinal interneurons are important facilitators and modulators of motor, sensory, and
autonomic functions in the intact CNS. This heterogeneous population of neurons is now …

Intermittent hypoxia and neurorehabilitation

EJ Gonzalez-Rothi, KZ Lee, EA Dale… - Journal of applied …, 2015 - journals.physiology.org
In recent years, it has become clear that brief, repeated presentations of hypoxia [ie, acute
intermittent hypoxia (AIH)] can boost the efficacy of more traditional therapeutic strategies in …

[HTML][HTML] Restoration of breathing after opioid overdose and spinal cord injury using temporal interference stimulation

MD Sunshine, AM Cassarà, E Neufeld… - Communications …, 2021 - nature.com
Respiratory insufficiency is a leading cause of death due to drug overdose or neuromuscular
disease. We hypothesized that a stimulation paradigm using temporal interference (TI) could …

Acute spinal cord injury: tetraplegia and paraplegia in small animals

N Granger, D Carwardine - Veterinary clinics: small animal …, 2014 - vetsmall.theclinics.com
Videos of:(1) extension of the digits in response to stimulation of the plantar surface in a dog
following severe SCI;(2) 5-year-old male neutered paraplegic Dachshund showing evidence …

Intraspinal microstimulation and diaphragm activation after cervical spinal cord injury

LM Mercier, EJ Gonzalez-Rothi… - Journal of …, 2017 - journals.physiology.org
Intraspinal microstimulation (ISMS) using implanted electrodes can evoke locomotor
movements after spinal cord injury (SCI) but has not been explored in the context of …

Diaphragm electromyographic activity following unilateral midcervical contusion injury in rats

S Rana, GC Sieck, CB Mantilla - Journal of …, 2017 - journals.physiology.org
Contusion-type injuries to the spinal cord are characterized by tissue loss and disruption of
spinal pathways. Midcervical spinal cord injuries impair the function of respiratory muscles …

Activation of inspiratory muscles via spinal cord stimulation

AF DiMarco, KE Kowalski - Respiratory physiology & neurobiology, 2013 - Elsevier
Diaphragm pacing is a clinically useful modality providing artificial ventilatory support in
patients with ventilator dependent spinal cord injury. Since this technique is successful in …

The neural control of human inspiratory muscles

JE Butler, AL Hudson, SC Gandevia - Progress in brain research, 2014 - Elsevier
The neural control of inspiratory muscles can be assessed in human subjects by
measurement of the behavior of populations of single motor unit from the various inspiratory …

Enhancing neural activity to drive respiratory plasticity following cervical spinal cord injury

KM Hormigo, LV Zholudeva, VM Spruance… - Experimental …, 2017 - Elsevier
Cervical spinal cord injury (SCI) results in permanent life-altering sensorimotor deficits,
among which impaired breathing is one of the most devastating and life-threatening. While …

Electrical neuromodulation of the respiratory system after spinal cord injury

JT Hachmann, PJ Grahn, JS Calvert, DI Drubach… - Mayo Clinic …, 2017 - Elsevier
Spinal cord injury (SCI) is a complex and devastating condition characterized by disruption
of descending, ascending, and intrinsic spinal circuitry resulting in chronic neurologic …