Oligodendrocytes (OLGs) are generated late in development and myelination is thus a
tardive event in the brain developmental process. It is however maintained whole life long at …

Significant progress in understanding cancer pathogenesis, it remains one of the leading
causes of death after cardiovascular diseases. Similarly viral infections have emerged from …

There are three main aims for this collaborative study: 1. to add a FIX antigen value to the 4
th International Standard for Blood Coagulation Factors II, VII, IX and X, Plasma, Human …

Dimethyl fumarate (DMF; trade name Tecfidera) is an oral formulation of the fumaric acid
ester that is Food and Drug Administration approved for treatment of relapsing-remitting …

Summary The management of Evans Syndrome in children is challenging due to the lack of
evidence‐based data on treatment. Steroids, the first‐choice therapy, are successful in …

The medications used to treat HIV have reduced the severity of cognitive deficits; yet, nearly
half of adults with HIV still exhibit some degree of cognitive deficits, referred to as HIV …

JCV is a small (∼ 45 nm), non-enveloped, circular, double-stranded DNA genome,
arranged in 72 viral capsomeres with icosahedral symmetry (Tan et al., 2009a). The genome …

Progressive multifocal leukoencephalopathy is a viral encephalitis induced by the John
Cunningham (JC) virus, an ubiquitous neurotropic papovavirus of the genus polyomavirus …

Natalizumab (Nat) is a humanized monoclonal antibody used for the treatment of relapsing
multiple sclerosis (MS). Nat inhibits lymphocyte migration via the blood brain barrier (BBB) …

Objective: This study evaluated the efficacy and safety of ATL1102, an antisense
oligonucleotide that selectively targets the RNA for human CD49d, the α subunit of very late …