QSAR/QSPR models based on quantum chemistry for risk assessment of pesticides according to current European legislation
JJ Villaverde, B Sevilla-Morán… - SAR and QSAR in …, 2020 - Taylor & Francis
In Europe, agencies and official organizations involved in the pesticide control such as the
EFSA, ECHA, JRC and ECETOC or even the OECD are pointing out that the software tools …
EFSA, ECHA, JRC and ECETOC or even the OECD are pointing out that the software tools …
Organic compounds percutaneous penetration in vivo in man: Relationship to mathematical predictive model
A Burli, RM Law, J Rodriguez, HI Maibach - Regulatory Toxicology and …, 2020 - Elsevier
Human skin is a common pathway through which chemicals in our environment enter the
body. To aid with risk management of environmental chemicals, the US EPA utilizes …
body. To aid with risk management of environmental chemicals, the US EPA utilizes …
Dermal Absorption: Considerations on Risk Assessment, Drug Administration, and the Human Skin Microbiome
K Wend, L Lemoine, C Pieper - Drug Discovery and Evaluation: Safety and …, 2024 - Springer
The following chapter describes the human skin and its complexity. On the one hand, the
skin protects against external influences; on the other, it provides a large surface area for the …
skin protects against external influences; on the other, it provides a large surface area for the …
In Vitro Human Dermal Absorption Studies on Pesticides in Complex Mixtures: Investigation of Guidance Criteria and Possible Impact Parameters
C Pieper, N Engel, K Wend, C Kneuer, S Martin - Toxics, 2024 - mdpi.com
Pesticides must not pose unacceptable risks to human health, so risk assessments are
conducted before products are authorised. Dermal exposure is often the main route of …
conducted before products are authorised. Dermal exposure is often the main route of …
[HTML][HTML] In silico prediction of dermal absorption from non-dietary exposure to plant protection products
CJ Kuster, J Baumann, SM Braun, P Fisher… - Computational …, 2022 - Elsevier
An in silico model for predicting skin penetration of active ingredients formulated in plant
protection products (PPP) has been developed using random forests (machine learning …
protection products (PPP) has been developed using random forests (machine learning …
Integrated translation framework for endocrine disruptors in the area of computational toxicology
Physiologically based pharmacokinetic (PBPK) models consist of a series of mathematical
representations of biological tissues and physiological processes in the body of a target …
representations of biological tissues and physiological processes in the body of a target …
Interdisciplinary Collaboration between Environmental Health and Clinical Experts on Cancers and Infertility Associated with Exposure to Endocrine Disruptors
A Fucic, A Mantovani, L Montano - 2020 - books.rsc.org
An interdisciplinary approach is crucial for effective investigation of the etiology of diseases
associated with exposures to endocrine disrupting chemicals (EDCs). Historically, EDCs …
associated with exposures to endocrine disrupting chemicals (EDCs). Historically, EDCs …
[PDF][PDF] Dermal absorption of chemicals and toxicity-the role of filaggrin genetics
ER Liljedahl - 2021 - portal.research.lu.se
Dermal exposure to chemicals is an increasing problem, and daily we are exposed to
chemicals via the skin both in our occupations and from consumer products. The skin barrier …
chemicals via the skin both in our occupations and from consumer products. The skin barrier …