Advances in the development of new biomarkers for Alzheimer's disease

TO Klyucherev, P Olszewski, AA Shalimova… - Translational …, 2022 - Springer
Alzheimer's disease (AD) is a complex, heterogeneous, progressive disease and is the most
common type of neurodegenerative dementia. The prevalence of AD is expected to increase …

Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the …

P Lewczuk, P Riederer, SE O'bryant… - The world journal of …, 2018 - Taylor & Francis
In the 12 years since the publication of the first Consensus Paper of the WFSBP on
biomarkers of neurodegenerative dementias, enormous advancement has taken place in …

Clinical diagnosis of progressive supranuclear palsy: the movement disorder society criteria

GU Höglinger, G Respondek, M Stamelou… - Movement …, 2017 - Wiley Online Library
Background: PSP is a neuropathologically defined disease entity. Clinical diagnostic criteria,
published in 1996 by the National Institute of Neurological Disorders and Stroke/Society for …

Contribution of cerebrovascular disease in autopsy confirmed neurodegenerative disease cases in the National Alzheimer's Coordinating Centre

JB Toledo, SE Arnold, K Raible, J Brettschneider… - Brain, 2013 - academic.oup.com
Cerebrovascular disease and vascular risk factors are associated with Alzheimer's disease,
but the evidence for their association with other neurodegenerative disorders is limited …

Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers

CR Jack, DS Knopman, WJ Jagust… - The lancet …, 2013 - thelancet.com
In 2010, we put forward a hypothetical model of the major biomarkers of Alzheimer's disease
(AD). The model was received with interest because we described the temporal evolution of …

Metabolic network failures in Alzheimer's disease: A biochemical road map

JB Toledo, M Arnold, G Kastenmüller, R Chang… - Alzheimer's & …, 2017 - Elsevier
Abstract Introduction The Alzheimer's Disease Research Summits of 2012 and 2015
incorporated experts from academia, industry, and nonprofit organizations to develop new …

Association of cerebrospinal fluid neurofilament light protein levels with cognition in patients with dementia, motor neuron disease, and movement disorders

B Olsson, E Portelius, NC Cullen, Å Sandelius… - JAMA …, 2019 - jamanetwork.com
Importance Neuronal and axonal destruction are hallmarks of neurodegenerative diseases,
but it is difficult to estimate the extent and progress of the damage in the disease process …

[HTML][HTML] Appropriate use criteria for lumbar puncture and cerebrospinal fluid testing in the diagnosis of Alzheimer's disease

LM Shaw, J Arias, K Blennow, D Galasko… - Alzheimer's & …, 2018 - Elsevier
Abstract Introduction The Alzheimer's Association convened a multidisciplinary workgroup to
develop appropriate use criteria to guide the safe and optimal use of the lumbar puncture …

Association of cerebrospinal fluid β-amyloid 1-42, T-tau, P-tau181, and α-synuclein levels with clinical features of drug-naive patients with early Parkinson disease

JH Kang, DJ Irwin, AS Chen-Plotkin, A Siderowf… - JAMA …, 2013 - jamanetwork.com
Importance We observed a significant correlation between cerebrospinal fluid (CSF) levels
of tau proteins and α-synuclein, but not β-amyloid 1-42 (Aβ1-42), and lower concentration of …

Imaging and fluid biomarkers in frontotemporal dementia

LH Meeter, LD Kaat, JD Rohrer… - Nature Reviews …, 2017 - nature.com
Frontotemporal dementia (FTD), the second most common type of presenile dementia, is a
heterogeneous neurodegenerative disease characterized by progressive behavioural …