Proteins that self-assemble into polyhedral shell-like structures are useful molecular
containers both in nature and in the laboratory. Here we review efforts to repurpose diverse …

Dendritic cell (DC)‐based cancer immunotherapy has exhibited remarkable clinical
prospects because DCs play a central role in initiating and regulating adaptive immune …

Despite remarkable advances over the past several decades, many therapeutic
nanomaterials fail to overcome major in vivo delivery barriers. Controlling immunogenicity …

Immunotherapy is rapidly maturing towards extensive clinical use. However, it does not work
well in large patient populations because of an immunosuppressed microenvironment and …

As a DNA damaging agent, oxaliplatin (OXA) can induce immunogenic cell death (ICD) in
tumors to activate the immune system. However, the DNA damage induced by OXA is limited …

Recent years have seen enormous advances in nanovaccines for both prophylactic and
therapeutic applications, but most of these technologies employ chemical or hybrid semi …

Compartmentalization is an essential feature of all cells. It allows cells to segregate and
coordinate physiological functions in a controlled and ordered manner. Different …

Nanocages (NCs) have emerged as a new class of drug-carriers, with a wide range of
possibilities in multi-modality medical treatments and theranostics. Nanocages can …

The aggressive proliferation of tumor cells often requires increased glucose uptake and
excessive anaerobic glycolysis, leading to the massive production and secretion of lactate to …

Encapsulins are a recently discovered class of prokaryotic self-assembling icosahedral
protein nanocompartments measuring between 24 and 42 nm in diameter, capable of …