Tuberculosis (TB) is a leading cause worldwide of human mortality attributable to a single
infectious agent. Recent studies targeting candidate genes and “case-control” association …

The evidence for a human genetic component in susceptibility to tuberculosis (TB) is
incontrovertible. Quite apart from studies of rare disease events illustrating the importance of …

Abstract CC chemokine ligand 18 (CCL18) was originally discovered as pulmonary and
activation-regulated chemokine (PARC), dendritic cell (DC)-chemokine 1 (DC-CK1) …

Disseminated disease in children and pulmonary disease in adults constitute two major
epidemiological and clinical forms of tuberculosis. Paradoxically, only a small fraction of …

We examined the distribution of single nucleotide polymorphisms (SNPs) in nitric oxide
synthase 2A, monocyte chemoattractant protein–1 (MCP-1), regulated on activation, normal …

Despite the discovery of the tuberculosis (TB) bacillus over 100 years ago and the
availability of effective drugs for over 50 years, there remain a number of formidable …

Host genetic factors play a major role in determining differential susceptibility to major
infectious diseases of humans, such as malaria, HIV/AIDS, tuberculosis, and invasive …

We need to understand what is different about susceptibility to tuberculosis (TB) in
developing countries where most TB occurs, and where the current vaccine, Bacillus …

Tuberculosis (TB) is still remains the major threat for human health worldwide. Several case-
control, candidate-gene, family studies and genome-wide association studies (GWAS) …

Despite the availability of effective treatment for several decades, leprosy remains an
important medical problem in many regions of the world. Infection with Mycobacterium …