[HTML][HTML] Neurotransmitters—key factors in neurological and neurodegenerative disorders of the central nervous system
Neurotransmitters are molecules that amplify, transmit, and convert signals in cells, having
an essential role in information transmission throughout the nervous system. Hundreds of …
an essential role in information transmission throughout the nervous system. Hundreds of …
[HTML][HTML] Oligodendrocyte death and myelin loss in the cuprizone model: an updated overview of the intrinsic and extrinsic causes of cuprizone demyelination
M Zirngibl, P Assinck, A Sizov, AV Caprariello… - Molecular …, 2022 - Springer
Background The dietary consumption of cuprizone–a copper chelator–has long been known
to induce demyelination of specific brain structures and is widely used as model of multiple …
to induce demyelination of specific brain structures and is widely used as model of multiple …
Potential drug targets for multiple sclerosis identified through Mendelian randomization analysis
J Lin, J Zhou, Y Xu - Brain, 2023 - academic.oup.com
Multiple sclerosis is a complex autoimmune disease, and several therapies for multiple
sclerosis have been developed and widely used. However, existing medications for multiple …
sclerosis have been developed and widely used. However, existing medications for multiple …
Ponesimod compared with teriflunomide in patients with relapsing multiple sclerosis in the active-comparator phase 3 OPTIMUM study: a randomized clinical trial
Importance To our knowledge, the Oral Ponesimod Versus Teriflunomide In Relapsing
Multiple Sclerosis (OPTIMUM) trial is the first phase 3 study comparing 2 oral disease …
Multiple Sclerosis (OPTIMUM) trial is the first phase 3 study comparing 2 oral disease …
[HTML][HTML] Clinical applications of stem cell-derived exosomes
F Tan, X Li, Z Wang, J Li, K Shahzad… - Signal Transduction and …, 2024 - nature.com
Although stem cell-based therapy has demonstrated considerable potential to manage
certain diseases more successfully than conventional surgery, it nevertheless comes with …
certain diseases more successfully than conventional surgery, it nevertheless comes with …
Retinal applications of swept source optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA)
The advent of optical coherence tomography (OCT) revolutionized both clinical assessment
and research of vitreoretinal conditions. Since then, extraordinary advances have been …
and research of vitreoretinal conditions. Since then, extraordinary advances have been …
Applications of deep learning techniques for automated multiple sclerosis detection using magnetic resonance imaging: A review
Multiple Sclerosis (MS) is a type of brain disease which causes visual, sensory, and motor
problems for people with a detrimental effect on the functioning of the nervous system. In …
problems for people with a detrimental effect on the functioning of the nervous system. In …
Immune cell regulation of glia during CNS injury and disease
Glial cells are abundant in the CNS and are essential for brain development and
homeostasis. These cells also regulate tissue recovery after injury and their dysfunction is a …
homeostasis. These cells also regulate tissue recovery after injury and their dysfunction is a …
The role of TH17 cells in multiple sclerosis: Therapeutic implications
Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous
system (CNS) where immunopathology is thought to be mediated by myelin-reactive CD4+ T …
system (CNS) where immunopathology is thought to be mediated by myelin-reactive CD4+ T …
The mutual interplay of gut microbiota, diet and human disease
The intestinal milieu harbours the gut microbiota, consisting of a complex community of
bacteria, archaea, fungi, viruses and protozoans that bring to the host organism an …
bacteria, archaea, fungi, viruses and protozoans that bring to the host organism an …