Exosomes: Isolation, characterization, and biomedical applications

GN Alzhrani, ST Alanazi, SY Alsharif… - Cell Biology …, 2021 - Wiley Online Library
Exosomes are nano‐sized bioactive vesicles of 30–150 nm in diameter. They are secreted
by exocytosis of nearly all type of cells in to the extracellular fluid. Thereby, they can be …

Exosomes as biomarkers for female reproductive diseases diagnosis and therapy

S Esfandyari, H Elkafas, RM Chugh, H Park… - International journal of …, 2021 - mdpi.com
Cell–cell communication is an essential mechanism for the maintenance and development
of various organs, including the female reproductive system. Today, it is well-known that the …

Cancer‐associated fibroblast‐derived exosomal microRNA‐20a suppresses the PTEN/PI3K‐AKT pathway to promote the progression and chemoresistance of non …

L Shi, W Zhu, Y Huang, L Zhuo, S Wang… - Clinical and …, 2022 - Wiley Online Library
Abstract Background Cancer‐associated fibroblasts (CAFs) contributes to overall tumor
progression. In the current survey, we explored the ability of microRNA‐20a (miR‐20a) …

Genetics and inflammation in endometriosis: improving knowledge for development of new pharmacological strategies

E Giacomini, S Minetto, L Li Piani, L Pagliardini… - International journal of …, 2021 - mdpi.com
According to a rich body of literature, immune cell dysfunctions, both locally and
systemically, and an inflammatory environment characterize all forms of endometriosis …

MicroRNome analysis generates a blood-based signature for endometriosis

S Bendifallah, Y Dabi, S Suisse, L Jornea… - Scientific Reports, 2022 - nature.com
Endometriosis, characterized by endometrial-like tissue outside the uterus, is thought to
affect 2–10% of women of reproductive age: representing about 190 million women …

Omics-based novel strategies in the diagnosis of endometriosis

M Samare-Najaf, SA Razavinasab… - Critical Reviews in …, 2024 - Taylor & Francis
Endometriosis, an enigmatic and chronic disorder, is considered a debilitating condition
despite being benign. Globally, this gynecologic disorder affects up to 10% of females of …

Liquid biopsy in endometriosis: a systematic review

C Ronsini, P Fumiento, I Iavarone, PF Greco… - International Journal of …, 2023 - mdpi.com
Despite laparoscopy being a standardized option to diagnose pelvic endometriotic implants,
non-invasive biomarkers are necessary to avoid the discomfort of invasive procedures …

Non-invasive diagnosis of endometriosis: Immunologic and genetic markers

SM Mahini, M Younesi, G Mortazavi, M Samare-Najaf… - Clinica Chimica …, 2023 - Elsevier
Endometriosis, a benign gynecologic and chronic inflammatory disease, is defined by the
presence of endometrial tissue outside the uterus characterized mainly by pelvic pain and …

A promising future for endometriosis diagnosis and therapy: extracellular vesicles-a systematic review

S Scheck, ESJ Paterson, CE Henry - Reproductive Biology and …, 2022 - Springer
Endometriosis is a chronic, inflammatory gynaecological disease that can have severe
negative impacts on quality of life and fertility, placing burden on patients and the healthcare …

Exosomal lncRNA ROR1-AS1 derived from tumor cells promotes glioma progression via regulating miR-4686

Y Chai, HT Wu, CD Liang, CY You… - International Journal of …, 2020 - Taylor & Francis
Objective Glioma is one of the most common central nervous system malignant tumors,
accounting for 45%–60% of adult intracranial tumors. However, the clinical treatment of …