[HTML][HTML] Therapeutic monoclonal antibody therapies in chronic autoimmune demyelinating neuropathies

C Briani, A Visentin - Neurotherapeutics, 2022 - Elsevier
Autoimmune diseases of the peripheral nervous system have so far been treated mainly with
exogenous high-dose intravenous immunoglobulins (IVIg), that act through several …

Neurological complications of conventional and novel anticancer treatments

P Alberti, A Salvalaggio, AA Argyriou, J Bruna… - Cancers, 2022 - mdpi.com
Simple Summary Cancer survivors can experience neurological complications after
exposure to anticancer therapy. Chemotherapy-induced peripheral neurotoxicity (CIPN) …

Waldenström macroglobulinemia: 2023 update on diagnosis, risk stratification, and management

MA Gertz - American journal of hematology, 2023 - Wiley Online Library
Abstract Disease Overview Waldenström macroglobulinemia (WM) is a lymphoplasmacytic
lymphoma with immunoglobulin M (IgM) monoclonal protein. Clinical features include …

Mutational Profile in 75 Patients With Anti–Myelin-Associated Glycoprotein Neuropathy: Clinical and Hematologic Therapy Response and Hints on New Therapeutic …

F Castellani, A Visentin, E Schirinzi… - Neurology …, 2023 - AAN Enterprises
Background and Objectives Neuropathy with antibodies to myelin-associated glycoprotein
(MAG) is the most common paraproteinemic IgM neuropathy. Recently, the mutational profile …

Repurposing MS immunotherapies for CIDP and other autoimmune neuropathies: unfulfilled promise or efficient strategy?

F Kohle, MC Dalakas… - Therapeutic Advances in …, 2023 - journals.sagepub.com
Despite advances in the treatment of chronic inflammatory demyelinating
polyradiculoneuropathy (CIDP) and other common autoimmune neuropathies (AN), still …

The BCL2 inhibitor venetoclax plus rituximab is active in MYD88 wild-type polyneuropathy with anti-MAG antibodies

C Briani, A Visentin, F Castellani… - Neurology …, 2022 - AAN Enterprises
Objectives Ibrutinib is active in anti–myelin-associated glycoprotein (MAG) polyneuropathy
with MYD88L265P mutation; however, its efficacy is likely to be low in MYD88 wild-type …

Clinical trials of the BTK inhibitors ibrutinib and acalabrutinib in human diseases beyond B cell malignancies

S Zhu, J Jung, E Victor, J Arceo, S Gokhale… - Frontiers in …, 2021 - frontiersin.org
The BTK inhibitors ibrutinib and acalabrutinib are FDA-approved drugs for the treatment of B
cell malignances. Both drugs have demonstrated clinical efficacy and safety profiles superior …

From biology to treatment of monoclonal gammopathies of neurological significance

A Visentin, S Pravato, F Castellani, M Campagnolo… - Cancers, 2022 - mdpi.com
Simple Summary The peripheral nervous systems may be involved by several
hematological diseases ranging from preneoplastic diseases to overt malignancies or …

Update on therapy of chronic immune-mediated neuropathies

C Briani, D Cocito, M Campagnolo, PE Doneddu… - Neurological …, 2021 - Springer
Chronic immune-mediated neuropathies, including chronic inflammatory demyelinating
polyradiculoneuropathy (CIDP), neuropathies associated with monoclonal gammopathy …

Therapies in autoimmune peripheral neuropathies beyond intravenous immunoglobulin, plasma exchange and corticosteroids: An analytical review

A Sivadasan, V Bril - Transfusion Medicine Reviews, 2022 - Elsevier
Autoimmune neuropathies are often treatable. First-line immunotherapies include
intravenous immunoglobulin (IVIG), plasma exchange and corticosteroids. However, nearly …