4004 ESC Guidelines label use of medication should be limited to situations where it is in
the patient's interest to do so, with regard to the quality, safety, and efficacy of care, and only …

Studies in cardiology often record the time to multiple disease events such as death,
myocardial infarction, or hospitalization. Competing risks methods allow for the analysis of …

Clinical decision-making often relies on a subject's absolute risk of a disease event of
interest. However, in a frail population, competing risk events may preclude the occurrence …

Abstract Aims The EUropean Comparative Effectiveness Research to Assess the Use of
Primary ProphylacTic Implantable Cardioverter-Defibrillators (EU-CERT-ICD), a prospective …

Patients with cardiac diseases or conditions with high risk of developing cardiac diseases
undergo risk assessment by cardiologists, primary care physicians, and scientists based on …

ICD in Cardiac Amyloidosis Background Cardiac amyloidosis (CA) is associated with
increased risk of sudden cardiac arrest. Although ICD therapy improves survival in patients …

Sudden cardiac death is a major public health issue in Canada. However, despite the
overwhelming evidence to support the use of implantable cardioverter defibrillators (ICDs) in …

Aims Most patients who receive implantable cardioverter defibrillators (ICDs) for primary
prevention do not receive therapy during the lifespan of the ICD, whilst up to 50% of sudden …

Importance Implantable cardioverter-defibrillators (ICDs) have revolutionized the approach
to the prevention of sudden cardiac death and are commonly used in a wide range of high …

Predicting the occurrence of an adverse event over time is an important issue in clinical
medicine. Clinical prediction models and associated points‐based risk‐scoring systems are …