[HTML][HTML] Pathophysiology and therapeutic approaches for spinal cord injury

R Lima, A Monteiro, AJ Salgado, S Monteiro… - International Journal of …, 2022 - mdpi.com
Spinal cord injury (SCI) is a disabling condition that disrupts motor, sensory, and autonomic
functions. Despite extensive research in the last decades, SCI continues to be a global …

[HTML][HTML] Dental pulp stem cell-derived secretome and its regenerative potential

JK Bar, A Lis-Nawara, PG Grelewski - International journal of molecular …, 2021 - mdpi.com
The therapeutic potential of the dental pulp stem (DSC) cell-derived secretome, consisting of
various biomolecules, is undergoing intense research. Despite promising in vitro and in vivo …

[HTML][HTML] Mesenchymal stem cell-based therapy for stroke: current understanding and challenges

W Li, L Shi, B Hu, Y Hong, H Zhang, X Li… - Frontiers in Cellular …, 2021 - frontiersin.org
Stroke, the most prevalent cerebrovascular disease, causes serious loss of neurological
function and is the leading cause of morbidity and mortality worldwide. Despite advances in …

[HTML][HTML] High-throughput spatiotemporal monitoring of single-cell secretions via plasmonic microwell arrays

S Ansaryan, YC Liu, X Li, AM Economou… - Nature Biomedical …, 2023 - nature.com
Methods for the analysis of cell secretions at the single-cell level only provide
semiquantitative endpoint readouts. Here we describe a microwell array for the real-time …

[HTML][HTML] Mechanisms of stem cell therapy in spinal cord injuries

M Shinozaki, N Nagoshi, M Nakamura, H Okano - Cells, 2021 - mdpi.com
Every year, 0.93 million people worldwide suffer from spinal cord injury (SCI) with
irretrievable sequelae. Rehabilitation, currently the only available treatment, does not …

[HTML][HTML] Omics-based investigations of breast cancer

AN Neagu, D Whitham, P Bruno, H Morrissiey… - Molecules, 2023 - mdpi.com
Breast cancer (BC) is characterized by an extensive genotypic and phenotypic
heterogeneity. In-depth investigations into the molecular bases of BC phenotypes …

[HTML][HTML] Human pluripotent stem cell-derived ectomesenchymal stromal cells promote more robust functional recovery than umbilical cord-derived mesenchymal …

J Huang, F Yang, Z Ji, J Lin, Z Weng, LL Tsang… - Theranostics, 2022 - ncbi.nlm.nih.gov
Aims: Hypoxic-ischaemic encephalopathy (HIE) is one of the most serious complications in
neonates and infants. Mesenchymal stromal cell (MSC)-based therapy is emerging as a …

[HTML][HTML] Mesenchymal stromal cell secretome for traumatic brain injury: Focus on immunomodulatory action

F Pischiutta, E Caruso, H Cavaleiro, AJ Salgado… - Experimental …, 2022 - Elsevier
The severity and long-term consequences of brain damage in traumatic brain injured (TBI)
patients urgently calls for better neuroprotective/neuroreparative strategies for this …

[HTML][HTML] Tendon immune regeneration: insights on the synergetic role of stem and immune cells during tendon regeneration

V Russo, M El Khatib, G Prencipe, MR Citeroni… - Cells, 2022 - mdpi.com
Tendon disorders represent a very common pathology in today's population, and
tendinopathies that account 30% of tendon-related injuries, affect yearly millions of people …

[HTML][HTML] Secretome of stromal cancer-associated fibroblasts (CAFs): Relevance in cancer

D Mishra, D Banerjee - Cells, 2023 - mdpi.com
The cancer secretome reflects the assortment of proteins released by cancer cells.
Investigating cell secretomes not only provides a deeper knowledge of the healthy and …