[HTML][HTML] Pathophysiology and therapeutic approaches for spinal cord injury
Spinal cord injury (SCI) is a disabling condition that disrupts motor, sensory, and autonomic
functions. Despite extensive research in the last decades, SCI continues to be a global …
functions. Despite extensive research in the last decades, SCI continues to be a global …
[HTML][HTML] Dental pulp stem cell-derived secretome and its regenerative potential
JK Bar, A Lis-Nawara, PG Grelewski - International journal of molecular …, 2021 - mdpi.com
The therapeutic potential of the dental pulp stem (DSC) cell-derived secretome, consisting of
various biomolecules, is undergoing intense research. Despite promising in vitro and in vivo …
various biomolecules, is undergoing intense research. Despite promising in vitro and in vivo …
[HTML][HTML] Mesenchymal stem cell-based therapy for stroke: current understanding and challenges
W Li, L Shi, B Hu, Y Hong, H Zhang, X Li… - Frontiers in Cellular …, 2021 - frontiersin.org
Stroke, the most prevalent cerebrovascular disease, causes serious loss of neurological
function and is the leading cause of morbidity and mortality worldwide. Despite advances in …
function and is the leading cause of morbidity and mortality worldwide. Despite advances in …
[HTML][HTML] High-throughput spatiotemporal monitoring of single-cell secretions via plasmonic microwell arrays
Methods for the analysis of cell secretions at the single-cell level only provide
semiquantitative endpoint readouts. Here we describe a microwell array for the real-time …
semiquantitative endpoint readouts. Here we describe a microwell array for the real-time …
[HTML][HTML] Mechanisms of stem cell therapy in spinal cord injuries
Every year, 0.93 million people worldwide suffer from spinal cord injury (SCI) with
irretrievable sequelae. Rehabilitation, currently the only available treatment, does not …
irretrievable sequelae. Rehabilitation, currently the only available treatment, does not …
[HTML][HTML] Omics-based investigations of breast cancer
Breast cancer (BC) is characterized by an extensive genotypic and phenotypic
heterogeneity. In-depth investigations into the molecular bases of BC phenotypes …
heterogeneity. In-depth investigations into the molecular bases of BC phenotypes …
[HTML][HTML] Human pluripotent stem cell-derived ectomesenchymal stromal cells promote more robust functional recovery than umbilical cord-derived mesenchymal …
J Huang, F Yang, Z Ji, J Lin, Z Weng, LL Tsang… - Theranostics, 2022 - ncbi.nlm.nih.gov
Aims: Hypoxic-ischaemic encephalopathy (HIE) is one of the most serious complications in
neonates and infants. Mesenchymal stromal cell (MSC)-based therapy is emerging as a …
neonates and infants. Mesenchymal stromal cell (MSC)-based therapy is emerging as a …
[HTML][HTML] Mesenchymal stromal cell secretome for traumatic brain injury: Focus on immunomodulatory action
F Pischiutta, E Caruso, H Cavaleiro, AJ Salgado… - Experimental …, 2022 - Elsevier
The severity and long-term consequences of brain damage in traumatic brain injured (TBI)
patients urgently calls for better neuroprotective/neuroreparative strategies for this …
patients urgently calls for better neuroprotective/neuroreparative strategies for this …
[HTML][HTML] Tendon immune regeneration: insights on the synergetic role of stem and immune cells during tendon regeneration
V Russo, M El Khatib, G Prencipe, MR Citeroni… - Cells, 2022 - mdpi.com
Tendon disorders represent a very common pathology in today's population, and
tendinopathies that account 30% of tendon-related injuries, affect yearly millions of people …
tendinopathies that account 30% of tendon-related injuries, affect yearly millions of people …
[HTML][HTML] Secretome of stromal cancer-associated fibroblasts (CAFs): Relevance in cancer
D Mishra, D Banerjee - Cells, 2023 - mdpi.com
The cancer secretome reflects the assortment of proteins released by cancer cells.
Investigating cell secretomes not only provides a deeper knowledge of the healthy and …
Investigating cell secretomes not only provides a deeper knowledge of the healthy and …